Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Fibromatoses?

…al fibrosis Miscellaneous f Myofibromatosis; cicatricial f; hyaline f; postradiation f Hajdu SI. Non-neoplastic lesions. In: Differential Diagnosis of Soft Tissue and Bone Tumors. Philadelphia, PA: Lea & Febiger, 1986:32. “The fibroma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…rocytes present mostly in slits between spindle cells 7. No hyaline globules within endothelial cells 7. Hyaline globules within some endothelial cells 8. Extravasation of erythrocytes and deposits of hemosiderin in the stroma in loci 8. Extravas…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

…Another quaint remnant of times past is the term “toxic hyaline,” which was applied not too many years ago by authors of all textbooks of dermatopathology to fibrin in the wall of venules in erythema elevatum diutinum. Additional images V…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…d lower levels of the dermis show endothelial proliferations, hyaline degeneration, fibrin plugs, and thrombosis. A perivascular hemorrhage may be present. Because of the absence of polymorphonuclear neutrophils, this is not a vasculitis but a vascul…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apoptosis?

…erred to in times past as Civatte bodies, colloid bodies, and hyaline bodies (pathologic cell death). Those bodies, on the basis of findings observed in sections stained conventionally by hematoxylin and eosin, can be identified as necrotic keratocyt…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…0;Civatte bodies,” “colloid bodies,” “hyaline bodies,” “apoptotic bodies,” “sunburn cells,” and “satellite cells.” Click image to enlarge. + Homogenous eosinophilic globules in dermal…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Endothelial Swelling?

…s such as fibrinoid necrosis, necrosis of collagen, and toxic hyaline, and on which should be thrown eczema, parapsoriasis, and dysplasia. The gerund swelling implies progression and denotes an action that cannot be seen through a conventional micros…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

…l basophilic neutrophil necrosis, leucocytoclasia surrounding hyaline necrobiotic collagen foci, and peripheral histiocyte/macrophage granuloma.” Winkelmann RK, Connolly SM, Quimby SR, Mertz LE. Cutaneous Churg-Strauss syndrome: granuloma annu…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

…e.g., “fatty,” “mucinous,” and “hyaline degeneration.” Attributes common to “hot comb alopecia” and to “follicular degeneration syndrome” are said to be predominance in African-American wome…