A Clinical Atlas of 101 Common Skin Diseases

Palmar and Plantar Keratoderma

A keratotic condition of the palms and soles, inherited usually, but sometimes acquired, in which involvement may be diffuse, circumscribed (including striate), or punctate….

A Clinical Atlas of 101 Common Skin Diseases

Darier’s Disease

A genetically determined disorder in which numerous closely set keratotic papules are present on the skin, especially the trunk, in nail units, and on mucous membranes, particularly the palate, but also rarely in other parts of the gastrointestinal…

A Clinical Atlas of 101 Common Skin Diseases

Atypical Mycobacterial Infections

Infection of skin and subcutaneous tissue by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be punc…

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

“On the basis of clinical, histological, and cellular kinetic observations, a separation of the major ichthyosiform dermatoses into four groups is proposed. Ichthyosis vulgaris patients have dry skin and fine scales on their trunk and extremi…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…IS [Gk. orthos (straight) + keras (horn) + -osis (condition)]: Hyperkeratosis in which nuclei are absent from cornified cells. See HYPERKERATOSIS. PANNICULITIS [L. panniculus (a layer) + Gk. -itis (inflammation of)]: An inflammatory disease in which…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.23.1A: Perivascular dermatitis, psoriasiform + 10.23.1B: Orthokeratosis, hypergranulosis, acanthosis, proliferation of infundibular and eccrine ductal keratocytes, and coarse bundles of collagen in vertical streaks = Lichen simp…

Differential Diagnosis in Dermatopathology

Discussions

Epidermolytic hyperkeratosis and a plane wart share several findings histopathologic, among them being a papillated and thickened epidermis, hypergranulosis, and cells with pale cytoplasm within the epidermis. The terms “epidermolytic hyperker…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subacute Cutaneous Lupus Erythematosus?

“Hydropic degeneration of the epidermal basal cell layer and mononuclear cell infiltration around dermal blood vessels and appendages are constant features of both forms of cutaneous LE. The lesions of SCLE [subacute cutaneous lupus erythema…