Histologic Diagnosis of Inflammatory Skin Diseases

Images

…olliculorum and squames in a zone of suppuration = Suppurative infundibulitis of unknown cause Demodex, Pityrosporum, bacteria, sebum, squames, and cornified cells, as well as neutrophils of a suppurative infundibulitis are sent flying into the dermi…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…s are but a few days old. Figure 5.310 A&B. Suppurative infundibulitis, not suppurative folliculitis! Neutrophils present to overflowing in an infundibulum qualifies as suppurative infundibulitis, not as suppurative folliculitis, the infundibu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…inflammation indicates that the process began as a suppurative infundibulitis. Not surprisingly, pustules are a finding common clinical in rosacea. 10.94.3A: Infundibulitis, suppurative, and peri-infundibulitis, granulomatous + 10.94.3B: Hi…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…ally as “folliculitis” in actuality is suppurative infundibulitis, recognizing, full well, that the notion of folliculitis, infundibulitis, and hidradenitis, to mention only three examples, is flawed fundamentally; there can be dermatitis…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…., an expression of dermatophytosis that begins as suppurative infundibulitis and in which hyphae tend to parasitize cornified cells of hair, inner sheath, isthmus, and infundibulum. The fungi first induce suppurative infundibulitis and peri-infundib…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.60.1A: Perivascular dermatitis, interface, focally lichenoid + 10.60.1B: Obscuration of the dermoepidermal junction by lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, and compact orthokeratosis = Lichen planus, ear…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

Error: Abortive is an accurate modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lympho…

Differential Diagnosis in Dermatopathology

Acne vulgaris, erythematous papule vs. Rosacea, erythematous papule

An inflammatory process that results from the effects of a drug administered systemically, e.g., by ingestion, inhalation, injection, or application rectally, and manifested usually by lesions distributed widely and symmetrically. Any of the many ex…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.63.1A: Perivascular dermatitis, interface, vacuolar + 10.63.1B: Smudged appearance of the dermoepidermal junction, focally thinned epidermis, and plentiful mucin throughout the dermis = Lupus erythematosus, discoid ┬áThe presence…