Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ose cells are necrotic can be told by their nuclei being pyknotic. At a later time, no hint of outlines of glandular cells is discernible, the cells of them being necrotic totally. Note also necrosis of the epidermis as indicated by karyolysis….

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…. Extensive necrosis en masse of adipocytes; karyorrhexis and karyolysis striking 7. Necrosis of adipocytes manifested mostly by karyorrhexis; karyolysis present, but subtle 8. Membanous fat necrosis 8. No membranous fat necrosis 9. Marked sclero…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Chondrodermatitis Nodularis Helicis?

…to them may be perichondral sclerosis and signs of necrosis (karyolysis) of cartilage. In summary, chondrodermatitis nodularis helicis is neither a primary disease of cartilage nor even a primary disease of the skin itself, but a response to externa…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…mis indicates that the lesion was induced by injury external. Karyolysis and pink cytoplasm of some ballooned keratocytes are indications of necrosis. Neutrophils are sprinkled in the upper half of the epidermis, likely in response to necrosis of ker…

Differential Diagnosis in Dermatopathology

Discussions

…d by nuclear changes alone, i.e., pyknosis, karyorrhexis, and karyolysis. In a normal adipocyte, however, the tiny nucleus is pushed by huge quantities of intracytoplasmic lipid to the side of the cell and, therefore, a histopathologist must look els…