Search Results for: karyorrhexis

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat: Panniculitis

…epidermal spinous zone devoid utterly of spongiosis. In classic pathology, distinctive changes in nuclei, namely, pyknosis, karyorrhexis, and karyolysis, are indicators essential of necrosis. In fat lobules, however, most nuclei are missed as a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ier’s collections in mycosis fungoides, but the lymphocytes in this disease induced by a virus show signs of extensive karyorrhexis. 11.2.2A: Nodular and diffuse dermatosis + 11.2.2B: Abnormal lymphocytes in the dermis and in discrete…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…m vessels 6. Lymphocytes in the wall of small, medium-sized, and large vessels 7. Extensive necrosis en masse of adipocytes; karyorrhexis and karyolysis striking 7. Necrosis of adipocytes manifested mostly by karyorrhexis; karyolysis present, but…

Histologic Diagnosis of Inflammatory Skin Diseases

Leukocytoclastic vasculitis

…splay only superficial perivascular and interstitial infiltrates composed mostly of neutrophils, some of which show signs of karyorrhexis, i.e., nuclear “dust,” and erythrocytes extravasated in variable numbers. Those paltry findings,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…lightly more advanced than those pictured in Fig. 47-1, many keratocytes show signs of necrosis, in particular, pyknosis and karyorrhexis. 10.47.3A: Vesicular dermatitis, intraepidermal, acantholytic and ballooned + 10.47.3B: Keratocytes with…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrotizing Vasculitis?

…of the endothelium, fibrinoid necrosis of vessel walls, extravasation of erythrocytes, and an infiltrate of neutrophils with karyorrhexis of nuclei (i.e. leukocytoclasia) are major features of cutaneous small vessel vasculitis.” Barham KL,…

Subacute cutaneous lupus erythematosus onset preceded by Kikuchi-Fujimoto disease

Subacute cutaneous lupus erythematosus onset preceded by Kikuchi-Fujimoto disease

…vascular and perifollicular lymphocytic infiltrates with interface dermatitis (Figure 2) and superficial nuclear debris with karyorrhexis. Direct immunofluorescence failed to demonstrate immunoglobulin or complement deposits along the…

Differential Diagnosis in Dermatopathology

Discussions

…by the same criteria applicable to other cells. In other cells, necrosis is judged by nuclear changes alone, i.e., pyknosis, karyorrhexis, and karyolysis. In a normal adipocyte, however, the tiny nucleus is pushed by huge quantities of…