A Clinical Atlas of 101 Common Skin Diseases

Dermatofibroma

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…

Histologic Diagnosis of Inflammatory Skin Diseases

Keloid

…sence of neoplastic cells distinguishes it from that of a true keloids. Laboratory confirmation None exists. Cause and mechanism Keloids are a type of fibrosing dermatitis that follows on some form of injury to the dermis, e.g., rupture of a follicu…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…1866. Ketchum LD, Cohen IK, Masters FW. Hypertrophic scars and keloids. A collective review. Plast Reconstr Surg 1974;53:140-54. Kischer CW. Comparative ultrastructure of hypertrophic scars and keloids. Scan Electron Microsc 1984;(Pt 1):423-31. Niess…

Differential Diagnosis in Dermatopathology

Discussions

Keloids and hypertrophic scars have many findings histopathologic in common (e.g., fibroplasia, telangiectases, infiltrates of inflammatory cells, mucin) and, in some instances, attributes of what seem to be both keloid and hypertrophic scar may be…

Differential Diagnosis in Dermatopathology

Keloid vs. Hypertrophic scar

An inflammatory process that develops secondary to trauma, usually in the form of a penetrating injury or rupture of a follicle, and that proceeds through stages of granulation tissue with numerous extravasated erythrocytes, granulomatous inflammati…

Dermatology Practical & Conceptual

Nodules on the right ear

Case report A healthy 17-year-old boy with a one-year history of asymptomatic, slowly enlarging nodules affecting his right ear was seen. The patient’s past medical history was unremarkable, he was not immunosuppressed, he was not taking any d…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Fibrosing Dermatitis

See Fig. 5.350 A&B. Figure 5.350 Fibrosing dermatitis. A. Early. B. Late (sclerosis). Fibrosing dermatitis (as well as fibrosing peri-infundibulitis/perifolliculitis and fibrosing panniculitis) results, in every instance, from injury to nonep…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…

Histologic Diagnosis of Inflammatory Skin Diseases

Collagen

More than 70% of the dry weight of the normal dermis consists of collagen (Fig. 1.79). The major collagens are Type I and Type III. Type I collagen has a molecular mass of about 290 KDa and accounts for approximately 80% of the total amount of colla…