Therapeutic Strategies in Dermatology

Leprosy/Hansen’s Disease and Reactional States

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease)

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Raynaud’s Phenomenon/Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Mucha-Habermann Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Darier’s Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

Key Points Sarcoidosis is a multisystem inflammatory disease, characterized by non-caseating granulomas, which occurs in patients of all ages and ethnic groups. Patients require thorough evaluation for multisystem disease and close monitoring for t…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…diterranean or Eastern European Jewish extraction. Although visceral involvement is found in up to 70% of patients (primarily in the GI tract), this is usually asymptomatic, and only 20% of patients with classic KS die of their disease. For this reas

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…e accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been arrested at an early stage of activation and is functionally deficient. This disorder is classified as single-system disease, mul…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

Treatment First-line therapy: The first-line therapy for Darier’s disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Darier’s disease is systemic retinoids. Isotretinoin and acitretin are equal…