Search Results for: langerhans\' cells

Therapeutic Strategies in Dermatology

Seborrheic Dermatitis: Principles of Seborrheic Dermatitis Management

…he coexisting conditions described above, a seborrheic dermatitis-like picture can be the presenting feature of all forms of Langerhans’ cell histiocytoses and other rare inherited or congenital disorders (e.g., Hailey-Hailey disease, primary…

Langerhans cell histiocytosis-a case report

Langerhans cell histiocytosis-a case report

…gnosis of Langerhans cell histiocytosis (LCH) was made based on morphologic criteria and confirmed by positivity of abnormal Langerhans cells by anti-CD1a and anti-S100 immunostains and negativity for anti-CD68. Figure 2. (A) Slight bilateral…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign and Malignant Cells?

…k, NY: Churchill-Livingstone, 1990:9. “Principal Morphologic Differences Between Normal Cells and Cancer Cells: Benign Cells Cancer Cells” Koss LG. Morphologic characteristics of cancer cells. In: Diagnostic Cytology and its…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus Cells, Nevocytes, and Nevomelanocytes?

…. 2nd ed. St. Louis, MO: CV Mosby Co., 1990:551. “Nevocytic Nevi Synonyms: Nevocellular nevus, nevus cell nevus. Nevus cells, or nevocytes, are cells closely related to the melanocytes which also originate from the neural crest and are capable…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Invasion by Neoplastic Cells?

…:51. “The papillary dermal component of RGP [radial growth phase] melanomas consists of a mixture of anaplastic single cells and nests infiltrating fibrovascular stroma. The apparent ‘invasive’ nests of melanoma cells are typically…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Trichodiscoma Related to the Hair Disk and Merkel-Cell Neoplasm to Merkel Cells?

cells. The abnormal cells that compose it are neuroendocrine in nature, but that does not mean that they are aberrant Merkel cells. Merkel cells are conceded generally to reside in the epidermis and not in the dermis, yet most Merkel-cell carcinomas…

Histologic Diagnosis of Inflammatory Skin Diseases

Merkel Cells

…ar in fetal skin by the 16th week of gestation, and, unlike melanocytes, they do not come from the neural crest, and, unlike Langerhanscells, they do not come from the bone marrow; they originate in the epidermis itself, presumably from…

Differential Diagnosis in Dermatopathology

Dermatofibroma with "monster" cells vs. Malignant fibrous histiocytoma

A proliferation of abnormal Langerhanscells that may affect internal organs, e.g., the spleen, liver, and bone, sometimes with fatal outcome, as well as the skin, where lesions usually manifest themselves as purpuric papules or ulcers that…

Therapeutic Strategies in Dermatology

Candidiasis: Initial Evaluation

Initial Evaluation Candidiasis Intertriginous Oral Paronychia Differential diagnosis Inverse pityriasis rosea Deficiency dermatitis (such as zinc deficiency, aka acrodermatitis enteropathica) Allergic or irritant contact dermatitis Inverse…