Search Results for: leishmaniasis

An itching plaque

An itching plaque

…es worldwide, probably widely underreported, with estimated global annual incidence of 0.2 to 0.4 million cases for visceral leishmaniasis (VL), and 0.7 to 1.2 million cutaneous leishmaniasis (CL) [1]. While 90% of VL concentrate in six countries…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…have strong cell-mediated immunity and are successful in destroying the parasites, the result being expressed clinically as leishmaniasis recidivans. In contrast, the immune response in patients in whom a Th2 response prevails are unable to destroy…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…lichenoid + 10.56.2B: Lymphocytes, plasma cells, and histiocytes that contain tiny round monomorphous basophilic organisms = Leishmaniasis, acute The distinctive character of the organisms in the cytoplasm of histiocytes establishes the diagnosis as…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…kingly foamy, rather than granular, or subtly foamy, cytoplasm of histiocytes devoid of blue-gray cast. Disseminated anergic leishmaniasis differs from lepromatous leprosy because distinct organisms are identified readily in the cytoplasm of…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…tered in infectious diseases besides tuberculosis, among those being tuberculoid leprosy and the recidivans manifestation of leishmaniasis, and in noninfectious diseases such as rosacea and its variant, perioral/periocular dermatitis. Curiously, the…

Differential Diagnosis in Dermatopathology

Discussions

…infiltrates of inflammatory cells in lupus vulgaris do not involve small nerves in the dermis. The recidivans expression of leishmaniasis resembles more closely lupus vulgaris than it does tuberculoid leprosy. Episodically, lesions of sarcoidosis…

Differential Diagnosis in Dermatopathology

Tuberculoid leprosy vs. Sarcoidosis

An inflammatory process caused by Mycobacterium tuberculosis. In the skin, it may be primary as a consequence of direct inoculation (tuberculosis verrucosa cutis) or secondary to a focus of tuberculosis in another organ (the lung for lupus…

Histologic Diagnosis of Inflammatory Skin Diseases

Tuberculosis

…se entirely, such as rosacea. Erythema induration now is known as nodular vasculitis.   Differential diagnosis clinical Leishmaniasis of the noduloulcerative type is indistinguishable morphologically from tuberculous chancre and from syphilitic…