Dermatology Practical & Conceptual

From the Dermatologikum Hamburg

The patient A 61-year-old woman presented herself with a chronic and widespread eruption of erythematous papules, pustules, ulcers, and hyperpigmented scars (Figures 1A-E). She had a history of rheumatoid arthritis. Figures 1A-E. Clinical appeara…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

“Lymphocytic vasculitis can be inferred unequivocally if there are infiltrates of lymphocytes in and around the walls of venules accompanied by fibrin deposition in their walls or lumens, or both.” Carlson JA, Mihm MC, Leboit PE. Cutan…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

“The basic and essential histopathologic change in pityriasis lichenoides et varioliformis acuta is a vasculitis, differing from pityriasis lichenoides chronica, which is primarily a disease of the epidermis…Very important and never des…

Differential Diagnosis in Dermatopathology

Discussions

Allergic (leukocytoclastic) vasculitis and septic vasculitis have several attributes histopathologic in common, namely, signs of vasculitis, neutrophils in the dermal infiltrate, extravasated erythrocytes, and tendency to necrosis of the surface epi…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema elevatum diutinum

Erythema elevatum diutinum Presentation stereotypical Age and sex Any age, but usually young adults, women especially Distribution of lesions Symmetrical over joints especially, particularly the dorsa of the hands and the elbows and knees Shape of l…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Allergic (leukocytoclastic) vasculitis Septic vasculitis 1. Leukocytoclasis, i.e., nuclear “dust” of neutrophils invariable and abundant usually 1. No nuclear “dust” of neutrophils 2. Fibrin in and around the wall of ve…