Histologic Diagnosis of Inflammatory Skin Diseases

Macular and papular (lichenoid) amyloidosis-Cutaneous solely

Macular and papular (lichenoid) amyloidosis—Cutaneous solely Presentation stereotypical Age and sex Women of Asian, Latin, or Middle Eastern ancestry usually Distribution of lesions Macular form most common in the interscapular region, but also seen…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid discoid lupus erythematosus

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a syst…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid secondary syphilis

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a syst…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…superficial and deep. Figure 5.19 A. Interface dermatitis, lichenoid, superficial. B. Interface dermatitis, lichenoid, superficial and deep. Figure 5.20 A. Ballooning dermatitis, superficial. B. Ballooning dermatitis, superficial and deep….

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…recipitated by sunlight. Whether it is true lichen planus or a lichenoid photodermatitis has yet to be resolved, but we are not at all convinced that it is anything other than a lichenoid photodermatitis unrelated to authentic lichen planus. Differe…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…disease). 11.14.23A: Perivascular dermatosis, spongiotic lichenoid + 11.14.23B: Lymphocytes in the epidermis larger than those in the dermis and wiry bundles of collagen in zones of lichenoid infiltration = Mycosis fungoides, plaque  Two cl…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…hils sometimes present in the dermal infiltrate Lymphocytes in lichenoid array, if only focally; some dermal papillae may be stuffed with lymphocytes Wiry bundles of collagen arranged haphazardly in zones of lichenoid infiltration of lymphocytes Some…