Histologic Diagnosis of Inflammatory Skin Diseases

Macular and papular (lichenoid) amyloidosis-Cutaneous solely

Macular and papular (lichenoid) amyloidosis—Cutaneous solely Presentation stereotypical Age and sex Women of Asian, Latin, or Middle Eastern ancestry usually Distribution of lesions Macular form most common in the interscapular region, but also seen…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid discoid lupus erythematosus

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a syst…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid secondary syphilis

A condition in which deposits of a fibrillary protein (amyloid) appear in the skin as macules, papules, and nodules consequent to the effects of local factors, or as patches (which may be purpuric), plaques, nodules, and tumors as a result of a syst…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…superficial and deep. Figure 5.19 A. Interface dermatitis, lichenoid, superficial. B. Interface dermatitis, lichenoid, superficial and deep. Figure 5.20 A. Ballooning dermatitis, superficial. B. Ballooning dermatitis, superficial and deep. F…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ecipitated by sunlight. Whether it is true lichen planus or a lichenoid photodermatitis has yet to be resolved, but we are not at all convinced that it is anything other than a lichenoid photodermatitis unrelated to authentic lichen planus. Differen…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…Images 11.14.1A: Perivascular dermatosis, psoriasiform lichenoid + 11.14.1B: Lymphocytes, sparse in both the dermis and epidermis, larger in the epidermis than in dermis, solitary in the basal layer in foci, and in association with scant s…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…variably interstitial infiltrate of lymphocytes Subtle patchy lichenoid infiltration of lymphocytes not uncommonly Lymphocytes disposed as solitary units in some loci of the epidermal basal layer Lymphocytes sprinkled as solitary units in the epiderm…