Search Results for: lymphatics

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

Cutaneous and subcutaneous lesions, usually nodules, that have become keratotic, crusted, and ulcerated as a consequence of infection by a variety of deep fungi, i.e., fungi situated in the dermis and subcutis, some of which may be disseminated to…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…xclusively for dissemination of cells of a malignant neoplasm from a primary site by means of conduits (blood vessels and/or lymphatics) or across serosal surfaces. Error: Mid-dermal elastolysis is a specific type of atrophy distinct in itself….

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat

…gen, divide conglomerations of subcutaneous adipocytes into lobules. The fibrous septa also house muscle-containing vessels, lymphatics, and nerves. (x25) Arteries and veins in the subcutaneous fat are positioned within the major fibrous septa…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…4. Neoplastic cells never are restricted entirely to the deep part of the dermis 5. Neoplastic cells found sometimes within lymphatics 5. Neoplastic cells are present within lymphatics 6. Neoplastic cells not “basaloid,” i.e., their…

Differential Diagnosis in Dermatopathology

Discussions

…ical forms as follows: Inflammatory: red, edematous, and indurated (similar to that in erysipelas) because of obstruction of lymphatics by the neoplastic cells Telangiectatic: purple papules, nodules, and hemorrhagic patches and plaques that…

Histologic Diagnosis of Inflammatory Skin Diseases

Blood Vessels

…re, from edema that comes into being because of an imbalance between leakage of serum into tissues and reabsorption of it by lymphatics. A cutaneous vasculature that functions properly is crucial, too, to resolution of inflammatory reactions and…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

…nail units, melanocytes, Langerhans” cells, Merkel cells, structures of the dermoepithelial interface, blood vessels, lymphatics, collagen, elastic fibers, ground substance, muscles, and nerves. The strategy is to inform about how the skin…

Histologic Diagnosis of Inflammatory Skin Diseases

Destombes-Rosai-Dorfman disease

…sma cells, and neutrophils scattered among the predominant infiltrate of foamy histiocytes Foamy histiocytes in the lumen of lymphatics Differential diagnosis histopathologic Xanthomas lack signs of karyophagocytosis and are devoid of large numbers…

Histologic Diagnosis of Inflammatory Skin Diseases

Tuberculosis

…the effects of them. Extensive necrosis (caseation) and suppuration result. Concurrent with these events, the bacilli enter lymphatics and travel to lymph nodes in the region, where they ravage those structures. The combination of the primary site…