Histologic Diagnosis of Inflammatory Skin Diseases

Urticaria pigmentosa

…arier’s sign can be induced by vigorous rubbing. Diffuse mastocytosis is manifested as thickened, leathery, yellowish skin, whose folds are exaggerated. Systemic mastocytosis involves internal organs by infiltrates of mast cells. Mast cell leuk…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…n of leukocytoclastic vasculitis. Error: Urticaria pigmentosa, mastocytosis, and telangiectasia macularis eruptiva perstans are different names for different diseases. Reason: Urticaria pigmentosa and mastocytosis are synonyms, referring as they do t…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.23.1A: Perivascular and interstitial dermatosis + 11.23.1B: Mast cells predominate, telangiectases are accompanying in the upper part of the dermis, and the epidermis is hyperpigmented = Urticaria pigmentosa  This form of urtica…

Histologic Diagnosis of Inflammatory Skin Diseases

Histiocytosis X

Histiocytosis X Presentation stereotypical Age and sex Children, boys mostly, and also adults Distribution of lesions Localized or widespread Individual lesions Red papules, purpuric papules, erosions, and ulcers Course Protracted, if not treated; s…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Urticarial Vasculitis?

“Although necrotizing angiitis (vasculitis) of the superficial venules and capillaries of the skin is usually appreciated visually as a purpuric papule, a group of patients has been defined in whom all of the skin lesions were urticarial. Mic…