Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Epidemic of Melanoma?

…a recent increase in the incidence and mortality of cutaneous melanoma in the geriatric population (over 65 years). We are all grappling effectively with this present melanoma epidemic.” Fitzpatrick TB, Kenet RO. Reducing mortality and morbid…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Precursor Lesions of Melanoma?

“Precursors of melanoma are lesions that are benign per se but have the potential of turning malignant and thus giving rise to melanoma. Two such entities are recognized: (1) atypical nevomelanocytic proliferation, and (2) congenital nevomela…

Dermatology Practical & Conceptual

Nail matrix melanoma: consecutive cases in a general practice

Introduction Nail matrix melanoma, otherwise known as subungual melanoma, is unique in that the actual primary cutaneous melanoma is occult, being covered by the nail plate and the proximal nail fold. Fortunately, the concealed melanoma may produce…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Radial Growth Phase versus Vertical Growth Phase of Melanoma?

…s tumor.” Miller AJ, Mihm MC Jr. Mechanisms of disease: melanoma. N Engl J Med 2006;355:51. For more than three decades now, Clark and coworkers advanced the thesis that histopathologists are able to gauge prognosis of primary cutaneous melan…