Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

…as a papule or nodule which may become ulcerated. On the basis of clinico-pathologic correlation, five distinctive types of basal cell carcinoma have been identified, namely, nodular, superficial, morpheiform, fibroepithelial, and infundibulocystic….

Therapeutic Strategies in Dermatology

Lichen Planus: Key Points

…rarely of the skin, may be complicated by the development of squamous cell carcinoma. Lichen planus may be triggered by or found in association with exogenous factors, such as medications or contact allergens; a treatable cause should always be soug…

Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

…ing). Malignant melanoma, metastatic Differential Diagnosis Melanocytic nevi Basal cell carcinoma, especially pigmented variants of basal cell carcinoma. Amelanotic (non-pigmented) melanoma may al…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…in clusters on any anatomic site. When “primary,” B-cell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete staging has been performed. The major categories of primary cutaneou…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been arrest…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

…17;s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified involving the nipple of the breast, whi…

Therapeutic Strategies in Dermatology

Venous Stasis: Treatment

…pain control. Pitfalls A non-healing ulcer may be cutaneous carcinoma (basal cell, squamous cell, etc.) or an inflammatory ulcer (such as pyoderma gangrenosum). Biopsy non-healing ulcerations after three months of treatment or if there is concern f…

Therapeutic Strategies in Dermatology

Melanoma: Key Points

…ation with regional experts is recommended. New therapies for metastatic melanoma that are immunomodulatory or target melanoma signaling pathways (anti-CTLA4, anti-PD1, BRAF inhibitors) have significantly changed the management of metastatic melanoma…