Histologic Diagnosis of Inflammatory Skin Diseases

Dermatomyositis

…dermatomyositis or of discoid lupus erythematosus. If abundant mucin is noted in the reticular dermis, in addition to all the findings mentioned, differentiation still is not possible of dermatomyositis from discoid lupus erythematosus, mucin tending…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ar and interstitial dermatosis + 11.18.1B: Large amount of mucin in company with scattered spindle- and stellate-shaped fibrocytes, as well as mast cells = Scleromyxedema, early ┬áThis is an early lesion because mucin is so abundant in the reticul…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

…nical and histopathological features of reticular erythematous mucinosis syndrome (REM) who six years later developed diagnostic criteria for systemic lupus erythematosus (SLE). Two biopsies performed at the same area initially showed mucin dermal de…

Histologic Diagnosis of Inflammatory Skin Diseases

Interstitial granulomatous dermatitis with arthritis

…ils and eosinophils are not notable in granuloma annulare, and mucin is more prominent in that condition. When granuloma annulare involves the subcutaneous fat, it is characterized by palisaded granulomas in the center of which is abundant mucin, unl…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…lack skin” looks like parapsoriasis en plaques. Alopecia mucinosa (mycosis fungoides with epithelial mucinosis) consists of patches and plaques studded with infundibulocentric papules, the lesions having a predilection for the face, neck and sc…

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular fasciitis

…roplasia increases as granulation tissue is replaced by it and mucin decreases Correlation clinicopathologic The nodule or tumor consists of fibrosing granulation tissue seated well below the skin in the subcutaneous fat and fascia. Edema, mucin, an…

Differential Diagnosis in Dermatopathology

Pretibial myxedema vs. Scleromyxedema

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…

Differential Diagnosis in Dermatopathology

Granuloma annulare vs. Necrobiosis lipoidica

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…