Search Results for: mucin

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…thologically from lesions of polymorphous light eruption devoid of edema or from those of tumid lupus erythematosus in which mucin is scant. In our experience, however, lesions thought by clinicians to be examples of lymphocytic infiltration of…

Histologic Diagnosis of Inflammatory Skin Diseases

Nephrogenic fibrosing dermopathy

…the dermis of numerous large epithelioid or stellate procollagen-I positive dermal spindle cells associated with deposits of mucin and with thin elastic fibers oriented parallel to the epidermis. Large bundles of collagen contained CD-34 positive…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tered spindle- and stellate-shaped fibrocytes, as well as mast cells = Scleromyxedema, early This is an early lesion because mucin is so abundant in the reticular dermis. A synonym for the condition is papular mucinosis, another is lichen…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatomyositis

…t membrane, the changes are those of a more advanced stage of dermatomyositis or of discoid lupus erythematosus. If abundant mucin is noted in the reticular dermis, in addition to all the findings mentioned, differentiation still is not possible of…

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular fasciitis

…ssue Extravasated erythrocytes and siderophages often Late Fibroplasia increases as granulation tissue is replaced by it and mucin decreases Correlation clinicopathologic The nodule or tumor consists of fibrosing granulation tissue seated well below…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…ar epidermis appear as solitary units or in small collections Deposits of mucin in infundibular epithelium often (epithelial mucinosis of “alopecia mucinosis”) Comedo-like plugs of infundibula sometimes Eosinophils in the interstitium of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

…ns, 1997:524–46. “We report the case of a woman with clinical and histopathological features of reticular erythematous mucinosis syndrome (REM) who six years later developed diagnostic criteria for systemic lupus erythematosus (SLE). Two…

Histologic Diagnosis of Inflammatory Skin Diseases

Interstitial granulomatous dermatitis with arthritis

…changes are focal, not diffuse. Moreover, as a rule, neutrophils and eosinophils are not notable in granuloma annulare, and mucin is more prominent in that condition. When granuloma annulare involves the subcutaneous fat, it is characterized by…