Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…n the setting of a specific subtype of sarcoidosis, Löfgren’s syndrome, wherein patients present with fevers, arthritis/arthralgias, hilar adenopathy, and EN. This is almost invariably seen in Caucasian patients and portends a good prognosis; most pa…

Therapeutic Strategies in Dermatology

Behçet Syndrome: Overview

Overview BehÇet syndrome is a disorder of unknown cause characterized by oral and genital mucous membrane ulceration, erythema nodosum-like lesions, uveitis, and numerous other vascular, rheumatological, and gastrointestinal complications. Because t…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Treatment

…almic branch (V1) of the trigeminal nerve and the Ramsey-Hunt syndrome (facial palsy and herpes zoster oticus) are exceptions where oral antiviral therapy is indicated. Significant zoster neuralgia is also a relative indication for antiviral therapy…

Therapeutic Strategies in Dermatology

Herpes Zoster & Varicella: Key Points

…d trimesters of pregnancy), resulting in congenital varicella syndrome, a syndrome marked by significant morbidity and mortality to both mother and child. Herpes zoster Herpes zoster represents the reactivation of VZV from the cranial or dorsal root…

Therapeutic Strategies in Dermatology

Cheilitis Granulomatosa: Overview

Melkersson-Rosenthal Syndrome Cheilitis granulomatosa is sudden onset of swelling of the lips which progresses to chronic enlargement. The Melkersson-Rosenthal syndrome diagnosis is made when lip enlargement is accompanied by facial paralysis or par…

Therapeutic Strategies in Dermatology

Appendigeal Tumors: Overview

…rtain adnexal tumors are cutaneous manifestations of inherited syndromes with significant internal associations (for example, trichilemmoma and Cowden’s syndrome; fibrofolliculoma and Birt-Hogg-Dube syndrome. Consider referral or consultation….

Therapeutic Strategies in Dermatology

Drug Eruptions: Therapy

…morbilliform rash may rarely be a prodrome of Stevens-Johnson syndrome or toxic epidermal necrolysis. Monitor for skin tenderness, bullous or target lesions, and mucosal involvement. When to refer to a dermatologist If the diagnosis of drug eruptio…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Clinical Cases

…red on trunk without mucosal lesions Diagnosis: favor Sweet’s syndrome A skin biopsy to confirm the diagnosis is performed. Concern for an underlying inflammatory condition or malignancy triggers a diagnostic evaluation including age-appropriate canc…

Therapeutic Strategies in Dermatology

Pernio/Chilblains: Treatment

…ders including cryoglobulinemia or anti-phospholipid antibody syndrome. Pitfalls Chilblain lupus erythematosus may present with lesions identical to idiopathic chilblain (pernio). Patients with lesions that fail to resolve with warming or that pers…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…7:46–56. “Eosinophilic cellulitis (Wells’ syndrome) is an inflammatory dermatosis characterized by marked eosinophilic infiltrates. Drugs and various infections are recognized causes of eosinophilic cellulitis.” Hirsch K, Lu…