Search Results for: necrobiosis

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiosis lipoidica

A granulomatous inflammatory process characterized clinically by patches that become yellowish plaques and that in time resolve with atrophy and telangiectases. The condition usually occurs in persons with diabetes.

Therapeutic Strategies in Dermatology

Granuloma Annulare: Key Points

Key Points Granuloma annulare is a reactive inflammatory skin condition, which commonly presents as annular pink, erythematous thin plaques on the distal extremities. Granuloma annulare usually presents as localized disease, generalized plaques or…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ar and interstitial dermatitis + 10.67.4B: Histiocytes, some multinucleate, in patchy distribution along vascular plexuses = Necrobiosis lipoidica The infiltrate of histiocytes in necrobiosis lipoidica tends to be arranged in distinct tiers that…

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat: Panniculitis

…generated collagen, as evidenced by the specialized stain that employs colloidal iron (C&D), certifies this condition as necrobiosis lipoidica. Figure 5.397 A&B. Necrobiosis lipoidica: both dermal and subcutaneous. Necrobiosis lipoidica,…

Differential Diagnosis in Dermatopathology

Discussions

…y never occurs. The two diseases under discussion in this chapter have in common the idea, reflected in the title, of “necrobiosis,” but the notion of necrobiosis itself is fallacious. The term implies life through death, a biologic…

Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids

Dermoscopy could be useful in differentiating sarcoidosis from necrobiotic granulomas even after treatment with systemic steroids

….3%) cases of cutaneous sarcoidosis. Those arborizing blood vessels might be shorter with fewer branches in sarcoidosis than necrobiosis lipoidica. Necrobiosis lipoidica is a rare disease. Bakos et al. [12], Pellicano et al. [11] and Lallas et al….

Differential Diagnosis in Dermatopathology

Discussions

…emonstrable in the center of palisaded granulomas and in zones where histiocytes are splayed in the interstitium, whereas in necrobiosis lipoidica none of it is detectable anywhere. In a very early lesion of granuloma annulare and of necrobiosis

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…d with various palisaded granulomatous inflammations of the skin and subcutaneous fat. Diverse diseases purported to display necrobiosis are granuloma annulare, necrobiosis lipoidica, necrobiotic xanthogranuloma, and rheumatoid nodule. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiotic xanthogranuloma

…s of unquestionable fat necrosis in the form of foam cells and cholesterol clefts, whereas the latter are not encountered in necrobiosis lipoidica. Moreover, the panniculitis in necrobiosis lipoidica is confined largely to septa affecting lobules…