Search Results for: necrosis

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat: Panniculitis

…. 5.401 A-E), none of them being dependent on findings in nuclei, but all, nonetheless, being indicative beyond doubt of fat necrosis: Figure 5.401 Five signs of necrosis of adipocytes. A. Granular fat necrosis. B. Fat “microcysts.” C….

Histologic Diagnosis of Inflammatory Skin Diseases

Poststeroid panniculitis

…that therapy for rheumatoid arthritis, rheumatic fever, or nephrotic syndrome. The mechanism is not known. Subcutaneous fat necrosis of the newborn probably occurs as a consequence of trauma during parturition. Comment Subcutaneous fat necrosis of…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…t necessarily indicative of vasculitis, as is evident, too, in other nonvasculitic conditions, such as zoster. Error: “Necrosis” of collagen, “necrosis” of the wall of small blood vessels, and “necrosis” of other…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…atitis, that condition resulting entirely from rubbing and scratching. No other cause, e.g., small-vessel vasculitis, of the necrosis pictured is apparent here. 10.23.12A: Perivascular dermatitis, slightly psoriasiform + 10.23.12B: Confluent…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…fat. Click image to enlarge. + Thrombi in most venules and capillaries, innumerable extravasated erythrocytes, and epidermal necrosis; few, if any, inflammatory cells = Disseminated intravascular coagulation/Coumarin necrosis/Thrombotic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…than as degeneration of that fibrous protein. Collagen is a fiber and, unlike the fibrocytes that produce it, cannot undergo necrosis; only viable cells can suffer necrosis. The tinctorial and structural changes in collagen observed in necrobiosis…