Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Invasion by Neoplastic Cells?

…invasion and invasive are applied only to cells of malignant neoplasms; never are they used to refer to the behavior of benign neoplasms. For example, it is standard practice in general pathology to describe neoplastic melanocytes of a primary melan…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nuclear Atypia, Cytoplasmic Atypia, and Architectural Atypia?

…uced as the hallmark for distinguishing malignant from benign neoplasms. Furthermore, nuclear atypia, no matter how it is defined, is not synonymous with malignancy biologic. That fact is manifested not only in benign neoplasms, such as Spitz’s…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

…ticular pattern . . .” Helwig EB. Seminar on the skin: neoplasms and dermatoses. In: Proceedings of the Twentieth Seminar of the International Congress of Clinical Pathology, Washington, D.C., September 11, 1954. Chicago, IL: American Society…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Borderline, Minimal Deviation, and Nevoid Melanomas?

…untered in other organ systems. In the category of epithelial neoplasms of the ovary, borderline lesions are common. They are also commonly manifested as papillary lesions of the breast.” Reed RJ. Minimal deviation melanoma. In: Mihm MC, Murphy…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Tricho-, pilo-, folliculo- ?

…lo-” appear often in titles of cutaneous hamartomas and neoplasms. To comprehend the meaning of those designations, it is requisite to understand what, precisely, is intended by pilo, tricho, and folliculo. Pilo- and tricho- are the Latin and G…

Dermatology Practical & Conceptual

The order of things and the classification of melanoma

…y different from classifying organisms. The classification of neoplasms as set forth by Virchow in the 19th century is also hierarchic and based on morphologic (in this case histogenetic) characteristics. According to the WHO classification there are…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…ar in inflammatory conditions, such as pemphigus vulgaris, in neoplasms, such as squamous-cell carcinoma (the so-called pseudoglandular type), and in cystic lesions, such as warty dyskeratoma. Acantholysis may be induced by the effects of (1) immunog…