Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nuclear Atypia, Cytoplasmic Atypia, and Architectural Atypia?

…duced as the hallmark for distinguishing malignant from benign neoplasms. Furthermore, nuclear atypia, no matter how it is defined, is not synonymous with malignancy biologic. That fact is manifested not only in benign neoplasms, such as Spitz’…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Invasion by Neoplastic Cells?

…s invasion and invasive are applied only to cells of malignant neoplasms; never are they used to refer to the behavior of benign neoplasms. For example, it is standard practice in general pathology to describe neoplastic melanocytes of a primary mela…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Borderline, Minimal Deviation, and Nevoid Melanomas?

…became au courant for general pathologists to diagnose certain neoplasms in several organs as “borderline malignancies,” the implication being that those neoplasms are somewhere between “benign” and “malignant.” No…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Tricho-, pilo-, folliculo- ?

…ch Dermatol 1961;83:606-618. “Classification of primary neoplasms of the hair follicle I. Neoplasms of the outer hair sheath Tricholemmoma a. clear cell type b. intermediate cell type.” Headington JT, French AJ. Primary neoplasms of the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

…tic tricholemmoma (Daniel Santa Cruz) as distinctive cutaneous neoplasms. We aver that those three conditions are not neoplasms, but hyperplasias of infundibula consequent to infection by papillomavirus. That judgment is verified by the diagnosis of…

Dermatology Practical & Conceptual

The order of things and the classification of melanoma

…anoma,” which belongs to the class of “melanocytic neoplasms,” which are part of the kingdom of “neuroectodermal neoplasms,” which belong to the universe of “neoplasms.” As science progresses, the era of morp…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…