Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

“Two forms [of blue nevus] exist, the rare being termed ‘cellular blue naevus.’ In the common variety bipolar and dendritic melanocytes lie singly or in masses in the dermis. . . . The cellular type is composed of the same element…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…iltrate of lymphocytes and histiocytes in and around cutaneous nerves and adnexal epithelium in the deep reticular dermis 4. No infiltrate of inflammatory cells in nerves or adnexal epithelium usually 5. Cutaneous nerves often missing consequent to…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.57.1A: Nodular dermatitis and panniculitis, granulomatous + 10.57.1B: Lymphocytes among dense infiltrates of slightly foamy histiocytes, some of them having a bluish cast + 10.57.1C + 10.57.1D = Leprosy, lepromatous…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Myxoma?

“myxoma (milk – s ? m?) [myxo – + G. -oma, tumor]. A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primiti…

Histologic Diagnosis of Inflammatory Skin Diseases

Introduction

Capability for accurate diagnosis of inflammatory skin diseases, clinically and histopathologically, requires familiarity thoroughly with embryologic, histologic, and anatomic aspects of the skin. Although examples of this precept are legion, only a…

Histologic Diagnosis of Inflammatory Skin Diseases

Nail Units

…rotect the terminal phalanges. A network of myelinated sensory nerves in the dermis of the nail bed, some nerves of which terminate near Merkel cells within the epithelium of the nail bed, enables the nail unit to contribute to appreciation of fine t…

Histologic Diagnosis of Inflammatory Skin Diseases

Sebaceous Units

A sebaceous gland, a lipid-producing epithelial structure, develops in the fourth month of fetal life from a protuberance of epithelium that lies between the uppermost protrusion, which represents the future apocrine unit, and the lower bulge, which…

Dermatology Practical & Conceptual

Dermoscopic findings in a patient with multiple piloleiomyomas

Abstract Piloleiomyoma can manifest itself as a pigmented lesion and part of the differential diagnosis with other pigmented skin lesions. However, we are not aware of previous descriptions in the literature of the dermoscopic features of piloleiomy…

Histologic Diagnosis of Inflammatory Skin Diseases

Langerhans’ Cells

Langerhans’ cells, named for Paul Langerhans who, while a medical student in Berlin in 1868, was the first to describe them, are dendritic cells that reside just above the middle of the spinous zone of the epidermis. They make their appearance…