Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

…tic Differential Diagnosis Melanocytic nevi Basal cell carcinoma, especially pigmented variants of basal cell carcinoma. Amelanotic (non-pigmented) melanoma may also clinically mimic basal cell carcinoma. Squamous cel…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…in clusters on any anatomic site. When “primary,” B-cell lymphomas of the skin seem to be wholly cutaneous with no evidence of extracutaneous manifestations after complete staging has been performed. The major categories of primary cutaneou…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

Overview Langerhans cell histiocytoses (Class I histiocytosis) are a group of disorders most common in childhood due to the accumulation or proliferation of a clonal population of cells bearing the phenotype of a Langerhans cell that has been arrest…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

…17;s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified involving the nipple of the breast, whi…

A Clinical Atlas of 101 Common Skin Diseases

Nevus Sebaceus

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

Overview Therapy of cutaneous T-cell lymphoma often requires specialized knowledge, and for this reason it is often appropriate to refer such patients to a medical center with specialized knowledge in the management of CTCL. Since early aggressive t…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…Overview Kaposi’s sarcoma (KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The…