Histologic Diagnosis of Inflammatory Skin Diseases

Rheumatoid nodule

Rheumatoid nodule Presentation stereotypical Age and sex Children and adults, more often females Distribution of lesions Near joints, especially elbows, and along bony structures, particularly extensor surfaces of forearms Individual lesions Nodules…

Histologic Diagnosis of Inflammatory Skin Diseases

Rheumatoid nodule

…A patch may become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nodule or tumor. The surface of an elevated lesion of melanoma tends to be uneven. When a melanoma is no longer flat, it has capability to met…

A Clinical Atlas of 101 Common Skin Diseases

Basal Cell Carcinoma

…n embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of clinico-pathologic correlation, five distinctive types of basal cell carcinoma have been identified, namely, nodular, superficial, morphe…

Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

Initial Evaluation Melanoma¬†frequently presents as an asymmetric pigmented lesion with an irregular scalloped border and uneven pigmentation. Some of the lesions are marked by hypopigmented areas (signifying areas of regression) or more darkly pigme…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…dular dermatitides the infiltrates are dense, i.e., they form nodules many times more replete with cells than are the infiltrates of a perivascular dermatitis. The nodules, just like their much less robust counterparts in perivascular dermatitis, are…

Differential Diagnosis in Dermatopathology

Discussions

…neous fat mostly have many findings in common with rheumatoid nodule. Both diseases are associated with epithelioid histiocytes arrayed in a palisade around zones of degenerated collagen, mucin, and fibrin, and both are accompanied at times by fibrop…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…aded arrangement around a huge deposit of fibrin = Rheumatoid nodule ¬†Neutrophils and nuclear “dust” of neutrophils scattered in the zone encircled by histiocytes in palisaded array, it being replete with fibrin, is typical of rheumatoid…