Search Results for: pale-cell acanthoma

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

A Clinical Atlas of 101 Common Skin Diseases

Lymphomas (Other Than Mycosis Fungoides and Lymphomatoid Papulosis)

…natomic site. Included among them are anaplastic large-cell lymphoma and panniculitis-like T-cell lymphoma. Anaplastic large-cell lymphoma of T-cell type usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…s universally by 3 months. Severe combined immunodeficiency syndrome and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

…ging or irritation. Intertrigo is a distinct inflammatory eruption affecting intertrigious sites that results from friction. Pale erythematous, macerated plaques are the clinical hallmarks of intertrigo, and they are typically KOH negative….

Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

…natomic site. Included among them are anaplastic large-cell lymphoma and panniculitis-like T-cell lymphoma. Anaplastic large-cell lymphoma of T-cell type usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express…

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Initial Evaluation

…litis, calcium deposition, thrombi, emboli, and cholesterol clefts. Often two biopsies are performed: one performed from the pale center of a fixed erythematous ring (in an attempt to capture the compromised blood vessel) and the other from a…

Large cell acanthoma: a debate throughout the decades

Large cell acanthoma: a debate throughout the decades

…is? Is it a distinct entity, a solar lentigo, a subtype of seborrheic keratosis, or an HPV-induced acanthoma? In 1970, large cell acanthoma (LCA) was first described by Pinkus, as a sharply demarcated, hyperkeratotic patch, often on sun-exposed…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

…natomic site. Included among them are anaplastic large-cell lymphoma and panniculitis-like T-cell lymphoma. Anaplastic large-cell lymphoma of T-cell type usually occurs as a solitary, rapidly growing tumor. Most of the neoplastic lymphocytes express…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…phagocytic, which includes circulating monocytes and tissue macrophages, and (2) dendritic, which includes Langerhans’ cells, dendritic cells, and interdigitating reticulum cells of lymph nodes. Langerhans’ cells differ from macrophages…