Search Results for: pale-cell acanthoma

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…s universally by 3 months. Severe combined immunodeficiency syndrome and graft vs. host disease may closely mimic Langerhans cell histiocytosis. In Langerhans cell histiocytosis, most patients are immunologically normal prior to therapy when…

Therapeutic Strategies in Dermatology

Candidiasis: Treatment

…ging or irritation. Intertrigo is a distinct inflammatory eruption affecting intertrigious sites that results from friction. Pale erythematous, macerated plaques are the clinical hallmarks of intertrigo, and they are typically KOH negative….

Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Therapeutic Strategies in Dermatology

Livedo / Livedoid Vasculopathy / Atrophie Blanche: Initial Evaluation

…litis, calcium deposition, thrombi, emboli, and cholesterol clefts. Often two biopsies are performed: one performed from the pale center of a fixed erythematous ring (in an attempt to capture the compromised blood vessel) and the other from a…

Large cell acanthoma: a debate throughout the decades

Large cell acanthoma: a debate throughout the decades

…is? Is it a distinct entity, a solar lentigo, a subtype of seborrheic keratosis, or an HPV-induced acanthoma? In 1970, large cell acanthoma (LCA) was first described by Pinkus, as a sharply demarcated, hyperkeratotic patch, often on sun-exposed…

Differential Diagnosis in Dermatopathology

"Pseudolymphoma," B-cell type vs. Malignant lymphoma, B-cell type

A malignant neoplasm made up of abnormal germinative cells analogous to those that compose the folliculosebaceous-apocrine germ in an embryo and that usually manifests clinically as a papule or nodule which may become ulcerated. On the basis of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

…phagocytic, which includes circulating monocytes and tissue macrophages, and (2) dendritic, which includes Langerhans’ cells, dendritic cells, and interdigitating reticulum cells of lymph nodes. Langerhans’ cells differ from macrophages…

Balloon cell melanoma in primary care practice: a case report

Balloon cell melanoma in primary care practice: a case report

…s [3]. The foamy cells are usually sparser in primary melanomas than subsequent metastases [3]. In contrast to balloon nevus cells, the cells of BCMM generally lack melanin [16]. Sparse quantities of melanin granules were only found in 9 cases of…