Therapeutic Strategies in Dermatology

Actinic Keratosis (a.k.a. Solar Keratosis): Initial Evaluation

Initial Evaluation Numerous actinic keratoses on sun-damaged skin are characterized by ill-defined hyperkeratotic erythematous papules or plaques. Actinic keratoses are commonly very thin and may lack erythema, and are best discerned clinically by p…

A Clinical Atlas of 101 Common Skin Diseases

Squamous Cell Carcinoma

…sm of keratinocytes that when present as a keratotic macule or papule on skin damaged badly by sunlight is referred to as solar keratosis. When present as a plaque it is termed Bowen’s disease, and when present as many papules in the anogenital…

A Clinical Atlas of 101 Common Skin Diseases

Dermatofibrosarcoma Protuberans

A malignant nonepithelial neoplasm (a sarcoma) presumably of perineural fibrocytes that presents itself usually on the trunk, but sometimes elsewhere, such as the extremities, face, and scalp. A papule of it tends to become a plaque, a nodule, a tum…

A Clinical Atlas of 101 Common Skin Diseases

Melanocytic Nevi and Melanotic Macules

Hamartomas (“congenital” melanocytic nevi) and benign neoplasms (“acquired” melanocytic nevi) of various specific types, all of which are composed of abnormal melanocytes and manifested clinically as lesions of different colo…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

Key Points Darier’s disease is a genodermatosis of autosomal dominant inheritance causing abnormalities of keratinization stemming from defects in calcium regulation in keratinocytes. The classic skin manifestation is an eruption of hyperkeratotic…

Therapeutic Strategies in Dermatology

Chondrodermatitis Nodularis Helicis: Clinical Cases

Clinical Case Case 1 70-year-old healthy man No significant past medical history Review of systems is noncontributory Social history is noncontributory; does not smoke or drink alcohol Presents for management of 4-month painful erosion on the he…

Therapeutic Strategies in Dermatology

Papular Urticaria: Treatment

Treatment First-line therapy: The first-line therapy for papular urticaria is to identify and eliminate the arthropod source and to then suppress the resultant inflammatory reaction. First-line management of the inflammatory reaction involves three…

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

…2014 Oliveira et al.] Figure 3. Dermoscopy observation (blue papule): homogeneous blue pattern. [Copyright: ©2014 Oliveira et al.] The blue papule was further examined by reflectance confocal microscopy (RCM) and high-definition optical coherence t…

Dermatology Practical & Conceptual

What is your diagnosis? A solitary purple papule on the arm

The patient A 54-year-old woman with immune thrombocytopenic purpura (ITP) referred to our dermatology department with a three-week-history of a purple-colored lesion on her right arm. The patient was on treatment with oral prednisone at 20 mg/day f…

A Clinical Atlas of 101 Common Skin Diseases

Chondrodermatitis Nodularis Helicis

A papule, sometimes eroded, ulcerated, crusted, or keratotic, on a helix or antehelix consequent to the effects of persistent trauma. Because a lesion of chondrodermatitis nodularis helicis results from the effects of external trauma, analogous to p…