Search Results for: pemphigoid

Therapeutic Strategies in Dermatology

Cicatricial Pemphigoid: Overview

Overview Cicatricial pemphigoid is a chronic, scarring, subepithelial bullous disorder that affects mucous membranes, including the conjunctivae. This disorder is thought to be mediated by autoantibodies directed at antigens in the epithelial…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Initial Evaluation

…lt is obtained. Pemphigus vulgaris Differential diagnosis IgA pemphigus Pemphigus foliaceus Paraneoplastic pemphigus Bullous pemphigoid Hailey-Hailey disease Oral aphthae Herpes simplex gingivostomatitis or Oral herpes zoster Erosive lichen planus…

Therapeutic Strategies in Dermatology

Pruritic Urticarial Papules and Plaques of Pregnancy: Treatment

…/kg in a single dose each morning) and rapidly taper to the lowest controlling dose. Pitfalls The early, urticarial phase of pemphigoid gestationis may resemble PUPPP. Pemphigoid gestationis may be associated with fetal morbidity (see above). A…

Therapeutic Strategies in Dermatology

Bullous Pemphigoid: Treatment

…re also considerations if systemic immunosuppression is not possible. Pitfalls Patients may rarely have drug-induced bullous pemphigoid, and careful evaluation of medication history is essential. Scabies infestation may mimic BP and clinicians…

Therapeutic Strategies in Dermatology

Linear IgA Dermatosis: Overview

Overview Linear IgA dermatosis is a bullous disorder that resembles dermatitis herpetiformis or bullous pemphigoid but is distinguished from these disorders by the linear deposition of IgA at the epidermodermal junction and the absence of…

Therapeutic Strategies in Dermatology

Chronic Bullous Disease of Childhood: Overview

…tching in association with linear deposition of IgA at the basement membrane zone. The clinical appearance resembles bullous pemphigoid. It often remits 2-3 years after onset and rarely lasts past age 10. Because this disorder affects children and…

A Clinical Atlas of 101 Common Skin Diseases

Herpes Gestationis

…arial papules and plaques accompanied by vesicles and bullae. Individual lesions are indistinguishable from those of bullous pemphigoid, clinically and histopathologically. Although the cause is not known, the mechanism is thought to be immunologic…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Key Points

…h decade of life. Childhood DH is rare. DH must be differentiated from other autoimmune blistering diseases, such as bullous pemphigoid, linear IgA dermatosis, pemphigus vulgaris, as well as scabetic or atopic disease. A skin biopsy, especially when…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Intitial Evaluation

…Initial Evaluation Differential Diagnosis Linear IgA dermatosis Bullous arthropod Bullous pemphigoid Pemphigus vulgaris Herpes zoster…

Therapeutic Strategies in Dermatology

Pemphigus Vulgaris & Paraneoplastic Pemphigus: Key Points

…dies, including those to plakin family components periplakin (190 kD), envoplakin (210 kD), desmoplakin II (210 kD), bullous pemphigoid antigen 1 (230 kD), desmoplakin 1 (250 kD), and plectin (500 kD), among others. The clinical presentation of…