Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.60.1A: Perivascular dermatitis, interface, focally lichenoid + 10.60.1B: Obscuration of the dermoepidermal junction by lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, and compact orthokeratosis = Lichen planus, ear…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Occlusion Triad?

“The follicular occlusion triad: (acne conglobata, hidradenitis suppurativa, and dissecting cellulitis of the scalp). These diseases comprise a generic group. Though not usually classified together, there is reason to believe that they are…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.37.1A: Pustular dermatitis, infundibular + 10.37.1B: Numerous Demodex folliculorum and squames in a zone of suppuration = Suppurative infundibulitis of unknown cause Demodex, Pityrosporum, bacteria, sebum, squames, and cornified…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.3.1A: Perifolliculitis (peribulbitis), lymphocytic + 10.3.1B: Infiltrates around the lower part of a follicle, i.e., the bulb, and each follicle being in the same stage of devolution = Alopecia areata In addition to lymphocytes…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

“An irreversible alopecia of the scalp occurs in negro women who straighten their hair with hot combs. The disease is common and distinctive, clinically and histopathologically. . . . Hot petrolatum used with the comb causes a chronic inflamm…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.25.1A: Perivascular dermatitis, interface, vacuolar + 10.25.1B: Lymphocytes around venules and along the dermoepidermal junction, many necrotic keratocytes, thin epidermis, hypergranulosis, and orthokeratosis = Drug eruption The…

Histologic Diagnosis of Inflammatory Skin Diseases

Majocchi’s granuloma

Majocchi’s granuloma Synonyms Nodular granulomatous perifolliculitis Tinea der unterschenkel Perifollicular granuloma Trichophytic granuloma Comment The term “Majocchi’s granuloma” is misleading because it implies that the…

Histologic Diagnosis of Inflammatory Skin Diseases

Hair Follicles

Morphologic and qualitative differences in hair, a cornified end-product of matrical cells positioned in the center of a follicular bulb, exist among the races of Man. In general, Caucasians have the most prominent hair, Asians have the least, and A…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

See Fig. 5.307 A&B. Figure 5.307 Pustular dermatitis. A. Infundibular. B. Surface epidermal. Although most pustules in skin are housed in infundibular epidermis (Fig. 5.308 A&B), many are lodged in surface epidermis (Fig. 5.309 A&B)….

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…