Therapeutic Strategies in Dermatology

Melanoma: Initial Evaluation

…red, purple). Nodular melanoma (NMM): Typically presents as a solitary nodule that arises from a pre-existing nevus or de novo. They may grow rapidly in thickness without radial spread (extension along the surface of the skin). Lentigo maligna melan…

Dermatology Practical & Conceptual

Spitz and Reed nevi: acquired or congenital?

…a survey on clinical, dermatoscopic and histopathologic clues suggesting a congenital origin of authentic Spitz nevi. Relevant differences in respect to Reed nevi are pointed out. What is a nevus? In classic pathology, the term nevus is usually rela…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

Abstract Melanoma arising in a nevus spilus is rare. There are two distinct types of nevus spilus characterized by macular or papular speckles, respectively. We report the case of a melanoma that arose in association with a giant nevus spilus maculo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus Cells, Nevocytes, and Nevomelanocytes?

“A nevus (mole) is a benign neoplasm of pigment-forming cells, the nevus cell.” Lookingbill DP, Marks JG Jr. Principles of clinical diagnosis. In: Moschella SL, Hurley HJ, eds. Dermatology. 3rd ed. Philadelphia, PA: WB Saunders Co., 19…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…orically, histologically, clinically and molecularly, that the so-called dysplastic nevus is a type of melanocytic nevus and should be managed like other types of melanocytic nevi [1,2]. This reinforces the notion set forth by the late Bernie Ackerma…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Basal-Cell Carcinoma Common in Nevus Sebaceus?

…us-cell carcinoma and basal-cell carcinoma arising in a naevus sebaceous of Jadassohn: case report and literature review. Clin Exp Dermatol 2005 May;30(3):259-60. Virtually every textbook in which an entry about nevus sebaceus is found states that b…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…(.25 inches) in diameter. Any mole that grows larger than that size may be cancerous.” Accessed November 29, 2006. “When a typical common nevus is seen under the microscope (one hopes