Histologic Diagnosis of Inflammatory Skin Diseases

Sarcoidosis

An inflammatory process, i.e., a panniculitis, marked by tender erythematous plaques, nodules, or tumors (or combinations thereof) that usually affect the anterior aspect of the legs and, less often, the arms, and induced by processes, in an organ o…

A Clinical Atlas of 101 Common Skin Diseases

Pernio

An inflammatory process that involves the acra, in particular fingers and toes, and sometimes the thighs with bluish red papules and nodules, which invariably is induced by cold. Chilblain is a synonym for pernio, which usually represents lupus eryt…

Therapeutic Strategies in Dermatology

Sweet’s Syndrome (Acute Febrile Neutrophil Dermatosis): Key Points

Key Points Indurated, often painful, erythematous nodules are the characteristic skin lesion that marks Sweet’s syndrome. Skin lesions may be bullous or cellulitis-like (pseudocellulitic) in appearance. Skin lesions of Sweet’s syndrome are often ac…

Therapeutic Strategies in Dermatology

Rosacea: Key Points

Key Points Rosacea has 4 different clinical presentations: erythemato-telangiectatic, papulo-pustular, phymatous, and ocular. It is essential to correctly identify the subtype of rosacea in order to select the appropriate medical or surgical therap…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…and the recidivans manifestation of leishmaniasis, but also in sarcoidosis. Moreover, necrosis of histiocytes sometimes may occur in the center of granulomas in sarcoidosis. 10.95.2A: Nodular dermatitis, granulomatous + 10.95.2B: Collection…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…cutis.” Figure 5.178 A&B. Sarcoidal granuloma in sarcoidosis. Nodules composed entirely of epithelioid histiocytes, devoid of lymphocytes and plasma cells, are findings expected in a stereotypical example of sarcoidosis such as this one…

Differential Diagnosis in Dermatopathology

Discussions

…more common in Africans and African-Americans. A rare form of sarcoidosis (Darier-Roussy type) is typified by granulomatous infiltrates in the subcutaneous fat. When lesions of sarcoidosis present themselves in the skin, the likelihood is that other…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

…sarcoidal granulomas because they are seen stereotypically in sarcoidosis, appear also in conditions as remote from sarcoidosis as silica granulomas and berylliosis. In a sense, lepromatous leprosy at times presents itself histopathologically as a t…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…riocular dermatitis. Curiously, the granulomas of subcutaneous sarcoidosis tend to be tuberculoid in character and, episodically, granulomas of sarcoidosis restricted to the dermis may be tuberculoid. When epithelial histiocytes are aligned in the ma…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…Quiz #377) Rosacea (Quiz #378) Rosacea (Quiz #661) Rosacea and sarcoidosis, concurrent (Quiz #379) Rosacea, extrafacial and facial (Quiz #494) Sarcoidosis (Quiz #196) Sarcoidosis (Quiz #380) Sarcoidosis (Quiz #385) Sarcoidosis (Quiz #602) Sarcoidosis