Differential Diagnosis in Dermatopathology

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Scleroderma (morphea) Scleredema (Buschke)…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Scleroderma (morphea) Scleredema (Buschke) 1. Dermis thickened slightly 1. Dermis thickened markedly, sometimes three or more times normal 2. Collagen bundles thickened markedly 2. Collagen bundles thickened only slightly 3. Collagen bundles…

Differential Diagnosis in Dermatopathology

Epidermolytic hyperkeratosis vs. Plane wart

A malignant neoplasm of keratinocytes that when present as a keratotic macule or papule on skin damaged badly by sunlight is referred to as solar keratosis. When present as a plaque it is termed Bowen’s disease, and when present as many papule…

Differential Diagnosis in Dermatopathology

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…as at sites of the plane warts. Giant condyloma acuminatum of Buschke-L–wenstein is a euphemism for verrucous squamous-cell carcinoma on the genitalia and, as the name suggests, is thought to arise in a pre-existing condyloma acuminatum. Carcinoma cu…