Differential Diagnosis in Dermatopathology

Spitz’s nevus, compound type vs. Melanoma

Papules, nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated…

Therapeutic Strategies in Dermatology

Erythema Multiforme: Key Points

Key Points Erythema multiforme (EM) is a clinical syndrome marked by either target lesions and/or mucosal erosions. It may be idiopathic or seen in association with infections or medications. EM has been reported in association with herpes simplex…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blue Nevus?

…he epidermis and the dermis. Our cumbersome definition of blue nevus fails, like all others, have failed and are doomed to fail, because it presumes, incorrectly, that blue nevus is a single process pathologic in which there are variations aplenty on…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nevus?

…08. “. . . nevoid [n?’void] is the adjective from nevus meaning like whatever nevus means.” Leider M, Rosenblum M. A dictionary of dermatological words, terms, and phrases. West Haven, CT: Dome Laboratories, 1976:296. “The…

Dermatology Practical & Conceptual

Blue nevus with a starburst pattern on dermoscopy

…etwork-like structures are also observed in some cases of blue nevus [4]. On the other hand, Spitz nevi usually present as solitary lesions on the lower extremities or the face. Clinically, a Spitz nevus is a rapidly growing pink-red or reddish-brown…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…lly, clinically and molecularly, that the so-called dysplastic nevus is a type of melanocytic nevus and should be managed like other types of melanocytic nevi [1,2]. This reinforces the notion set forth by the late Bernie Ackerman, who asserted more…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Normal, Typical, Ordinary, Banal, and Common Nevus?

…mmon) but, paradoxically, so-called dysplastic (Clark’s) nevus is more common by far than any so-called common nevus. Other melanocytic nevi, such as Unna’s, Miescher’s, and Spitz’s, also are common, but they are paltry in com…