Histologic Diagnosis of Inflammatory Skin Diseases

Images

…us pemphigoid, urticarial Eosinophils in the epidermis induce spongiosis that, at times, leads to formation of spongiotic vesicles. Uncommonly, a blister in bullous pemphigoid is entirely intraepidermal. 10.10.2A: Perivascular dermatitis, inter…

Histologic Diagnosis of Inflammatory Skin Diseases

Herpes gestationis

…mostly, but sometimes in tiny collections in conjunction with spongiosis Fully developed (vesicular) Perivascular and interstitial infiltrate of lymphocytes and many eosinophils Numerous eosinophils throughout the edematous upper part of the dermis…

Histologic Diagnosis of Inflammatory Skin Diseases

Polymorphous light eruption

…sually tethered to the dermis by gossamer strands of collagen Spongiosis of variable extent in some lesions; scale-crusts sometimes present, too Correlation clinicopathologic Papules are formed by superficial and deep perivascular infiltrates of lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…at times, by changes secondary to the effects of them such as spongiosis, acanthosis, and fibroplasia, but that infiltrate being unaffiliated with cells of any other fundamental pathologic process, such as neoplastic, hamartomatous, cystic, etc. INFI…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ans”, they being joined by a few lymphocytes in foci of spongiosis. 10.81.5A: Perivascular dermatitis, spongiotic psoriasiform + 10.81.5B: Lymphocytes, edema in dermal papillae, and scale-crusts = Pityriasis rosea, fully developed  Sp…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Apocrine Miliaria?

…rosyringia. At those sites can be noted often a tiny focus of spongiosis mediated by lymphocytes, and below the findings epidermal is a sparse, superficial perivascular and interstitial infiltrate of lymphocytes and neutrophils. Clinically, lesions o…

Histologic Diagnosis of Inflammatory Skin Diseases

Bullous pemphigoid

…mostly, but sometimes in tiny collections in conjunction with spongiosis Fully developed (vesicular) Perivascular and interstitial infiltrate of lymphocytes and many eosinophils Numerous eosinophils throughout the edematous upper part of the dermis…

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…ible Slight edema of the papillary dermis A discrete focus of spongiosis present sometimes in the epidermis at the very site of the “bite,” i.e., directly above the apex of the wedge formed by inflammatory cells whose vertex in the dermis…

Histologic Diagnosis of Inflammatory Skin Diseases

Mucha-Habermann disease

…mis, especially the lower half; range from few or many Slight spongiosis and ballooning Slight pallor in the upper part of the epidermis Cornified layer basket-weave in configuration Fully developed All of the features of early lesions plus: Wedge-…