Therapeutic Strategies in Dermatology

Raynaud’s Phenomenon/Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Leprosy/Hansen’s Disease and Reactional States

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Grover’s Disease / Transient Acantholytic Dermatosis

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Chronic Bullous Disease of Childhood

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Hailey-Hailey Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Sarcoidosis: Key Points

…ed, patients mount an inflammatory response, representing the onset of the disease. Putative antigens include an unknown autoantigen, misfolded serum amyloid A proteins, infectious agents (including mycobacteria or Propionibacterium acnes), particul…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…an Kaposi’s sarcoma African KS occurs in three forms in adults and children: localized cutaneous disease, localized aggressive disease (which may extend to underlying bone), and generalized disease. In areas endemic for HIV infection, AIDS-asso…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…nally deficient. This disorder is classified as single-system disease, multisystem disease, or multisystem disease with organ dysfunction. The skin is one of the most frequently affected organs in patients with both localized (skin only) and multisys…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

…tment First-line therapy: The first-line therapy for Darier’s disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Darier’s disease is systemic retinoids. Isotretinoin and acitretin are equally ef…