Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

Error: Abortive is an accurate modifier of particular pathologic processes, e.g., abortive dermatofibroma, abortive morphea, and abortive T-cell lymphoma. Reason: The idea itself is abortive! For example, what is called “abortive T-cell lympho…

Differential Diagnosis in Dermatopathology

Discussions

Photoallergic dermatitis and phototoxic dermatitis, as their names denote, are eruptions induced by ultraviolet light. The two conditions have features in common clinically and histopathologically, a situation that may pose problems in diagnosis for…

Histologic Diagnosis of Inflammatory Skin Diseases

Photoallergic dermatitis

Photoallergic dermatitis Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Sites exposed to sunlight especially, i.e., the face, the V region of the chest, forearms, and dorsa of hands; covered sites affected someti…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.53.1A: Perivascular dermatitis + 10.53.1B: Ballooned and individual necrotic keratocytes in the upper part of the epidermis = Phototoxic dermatitis In the realm of photodermatitis, the presence of many individual nec…

Differential Diagnosis in Dermatopathology

Photoallergic dermatitis vs. Phototoxic dermatitis

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…

Histologic Diagnosis of Inflammatory Skin Diseases

Miliaria crystallina

Miliaria crystallina Presentation stereotypical Age and sex Mostly in infants of both sexes, but also in elderly bedridden persons whose home is overheated Distribution of lesions Localized or widespread, especially at sites of recent sunburn Indivi…

Histologic Diagnosis of Inflammatory Skin Diseases

Toxic shock syndrome

Toxic shock syndrome Synonyms TSS Presentation stereotypical Age and sex Women using super-absorbent vaginal tampons especially, but possible in both sexes consequent to any infection by pathogenic bacteria, particularly Staphylococcus aureus, inclu…

Differential Diagnosis in Dermatopathology

Erythema multiforme vs. Graft-versus-host disease, acute phase

An inflammatory process that expresses itself in the skin in protean ways that are variations on a basic pathologic theme, and includes evanescent patches on the face (“butterfly blush”), scaly papules and plaques that resolve with atrop…