Search Results for: suppuration

Histologic Diagnosis of Inflammatory Skin Diseases

Subcutaneous Fat: Panniculitis

…esignation Majocchi’s granuloma fails to convey the manifold expressions morphologic of the process, they ranging from suppuration to fibroplasia. Figure 5.410 A&B. The cause of a distinctive lobular panniculitis: actinomyces. The…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ation in the skin. 10.38.10A: Nodular dermatitis, suppurative, and fibrosing dermatitis + 10.38.10B: A splinter in a zone of suppuration = Foreign body reaction to a splinter As a rule, foreign body reactions begin suppurative, end fibrotic, and in…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…enzymes released from polymorphonuclear leukocytes. Accumulation of pus in a cavity of a cavernous organ is called empyema. Suppuration in skin may manifest itself as tiny pustules (e.g., Munro’s microabscesses and Kogoj’s spongiform…

Histologic Diagnosis of Inflammatory Skin Diseases

α-1 antitrypsin deficiency

…subcutaneous tissue Late Ulceration deep Fibrosis in the panniculus adiposus Correlation clinicopathologic Fat necrosis and suppuration in lobules are responsible for the appearance of tender erythematous plaques and nodules. As the process becomes…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…Sulzberger-Garbe disease” is never made today, not even at NYU. Error: “Suppurative folliculitis” truly is suppuration in a follicle. Reason: What is termed “suppurative folliculitis” really is suppuration in…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…in pyoderma gangrenosum. 10.15.7A: Nodular and diffuse dermatitis, and panniculitis, septal and lobular + 10.15.7B: Foci of suppuration surrounded by histiocytes, some of them multinucleate, arranged in a palisade = Crohn’s disease Palisaded…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…changes pictured do not conform precisely, or even closely, to any well-defined panniculitis. That, as well as the prominent suppuration in a pattern bizarre, compels to a diagnosis of panniculitis induced factitiously. A diagnosis of factitious…

Histologic Diagnosis of Inflammatory Skin Diseases

Foreign body reaction

…by the presence of individual cornified cells (squames) in multinucleate histiocytes and of hair shafts either in a zone of suppuration or fibrosis, or surrounded by histiocytes. Splinters display a “stepladder” pattern typical of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…about whether the primary disease in the pancreas is pancreatitis or carcinoma. 10.73.2A: Panniculitis, lobular + 10.73.2B: Suppuration at the periphery of zones of granular fat necrosis and calcification of necrotic fat = Pancreatic panniculitis,…