Therapeutic Strategies in Dermatology

Hailey-Hailey Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Chronic Bullous Disease of Childhood

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease)

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Raynaud’s Phenomenon/Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Mucha-Habermann Disease

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

Therapeutic Strategies in Dermatology

Darier’s Disease: Treatment

Treatment First-line therapy: The first-line therapy for Dariers disease is systemic retinoids. First steps The currently accepted primary treatment of moderate-to-severe Dariers disease is systemic retinoids. Isotretinoin and acitretin are equal…

Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

…tomatic, and only 20% of patients with classic KS die of their disease. For this reason, therapy is often palliative and directed at control of local symptoms. Progressive disease may require more aggressive therapy. First Steps For localized or lim…

Therapeutic Strategies in Dermatology

Histiocytosis X/Langerhans Cell Histiocytoses: Overview

…notype of a Langerhans cell that has been arrested at an early stage of activation and is functionally deficient. This disorder is classified as single-system disease, multisystem disease, or multisystem disease with organ dysfunction. The skin is on…

Therapeutic Strategies in Dermatology

Darier’s Disease: Key Points

…bating factors include heat, humidity, UV light, perspiration, stress, and medications. Treatment should be adjusted accordingly and vigilant monitoring for superinfection is critical. Introduction Dariers disease is a genodermatosis of autosomal d…