Differential Diagnosis in Dermatopathology

Discussions

…that benign neoplasm made up overwhelmingly of trichoblasts. Trichoepithelioma is that type of trichoblastoma characterized by cribriform pattern formed by follicular germinative cells and by a tendency usually to limited differentiation in the form…

Dermatology Practical & Conceptual

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection

…(herpes virus), but also acantholytic dermatoses and tumors (trichoepithelioma and pleomorphic basal cell carcinoma). Histiocytic multinucleated giant cells in the epidermis can be observed in patients with either giant cell lichenoid dermatitis or…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Basal-Cell Carcinoma Common in Nevus Sebaceus?

…(40%); adnexal and pilar tumors (40%), such as tricholemmoma, trichoepithelioma, follicular or pilar hamartoma, proliferating pilar tumor, and sebaceous adenoma; and apocrine neoplasms (20%), such as apocrine adenoma, syringocystadenoma papilliferum,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudomalignancies?

…inoma or a squamous-cell carcinoma. For example, desmoplastic trichoepithelioma, a particular expression of trichoblastoma typified by columns of follicular germinative cells, often mimics a morpheiform basal-cell carcinoma histopathologically. The h…

Clinical Case Studies

Multiple Trichoepitheliomas

…mbers had similar lesions and carried a diagnosis of familial trichoepitheliomas. The patient had no other medical problems. Physical examination revealed numerous pink, 2- to 8-mm papules predominantly in a midface distribution (forehead, cheeks, ch…

Differential Diagnosis in Dermatopathology

Discussions

…mas tend to affect women more commonly than men. Desmoplastic trichoepithelioma also must be distinguished histopathologically from metastatic carcinoma of the breast to the skin and from morpheiform basal-cell carcinoma. The aspect crucial in this d…