Histologic Diagnosis of Inflammatory Skin Diseases

Miliary tuberculosis

Miliary tuberculosis Findings histopathologic Fully developed Sparse infiltrate of neutrophils Necrosis variable, often prominent Epidermis spared Stain for acid fast organisms reveals countless bacilli of M. tuberculosis Comment Miliary tuberculo…

Histologic Diagnosis of Inflammatory Skin Diseases

Tuberculosis verrucosa cutis

Tuberculosis verrucosa cutis Findings histopathologic Fully developed Granulomas dotting a lichenoid infiltrate of lymphocytes and plasma cells Beneath the zone of lichenoid lymphoplasmacytic infiltration, discrete granulomas surrounded by numerous…

Histologic Diagnosis of Inflammatory Skin Diseases

Tuberculosis

…l with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found, but when Mycobacterium tuberculosis is shown to be the agent responsible, the condition then is termed “erythema induratum.”…

A Clinical Atlas of 101 Common Skin Diseases

Erythema Nodosum

An inflammatory process, i.e., a panniculitis, marked by tender erythematous plaques, nodules, or tumors (or combinations thereof) that usually affect the anterior aspect of the legs and, less often, the arms, and induced by processes, in an organ o…

A Clinical Atlas of 101 Common Skin Diseases

Borreliosis (Lyme Disease)

An inflammatory disease caused by the spirochete Borrelia burgdorferi that manifests itself in the skin as erythematous lesions with figurate shapes, e.g., (round, ellipsoid, and arcuate) (erythema chronicum migrans), pseudolymphomatous nodules (lym…

A Clinical Atlas of 101 Common Skin Diseases

Atypical Mycobacterial Infections

…by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be punctuated by draining sinuses and by ulcers….

Therapeutic Strategies in Dermatology

Erythema Multiforme: Key Points

Key Points Erythema multiforme (EM) is a clinical syndrome marked by either target lesions and/or mucosal erosions. It may be idiopathic or seen in association with infections or medications. EM has been reported in association with herpes simplex…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…lobular panniculitis is thought to be caused by Mycobacterium tuberculosis; in actuality, what for a century have been termed “tuberculids” are a mix of granulomatous dermatitides and panniculitides that, in times past, were thought to be…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Subcutaneous Fat: Panniculitis

…03 A&B). When nodular vasculitis occurs in a patient with tuberculosis, it is given the name erythema induratum. Small-vessel vasculitis in the subcutaneous fat accompanied by leukocytoclasis of neutrophils, no matter how minute the amount of nuc…