Therapeutic Strategies in Dermatology

Kaposi’s Sarcoma: Overview

Overview Kaposi’s sarcoma (KS) results from endothelial cell proliferation caused by infection with human herpesvirus 8 and occurs in four settings: classic KS, African (endemic) KS, immunosuppressive-associated KS, and AIDS-associated KS. The…

Therapeutic Strategies in Dermatology

Erythema Annulare Centrifugum: Overview

Gyrate Erythemas, Figurate Erythemas, and Migratory Erythemas Gyrate erythemas are reactive processes. The therapeutic strategy is to determine and treat the underlying cause, and the cutaneous reaction is then cured. Underlying malignancy; dermatop…

Therapeutic Strategies in Dermatology

Psoriasis: References

References Carter JD, Ladhani A, Ricca LR, et al. (2009) A safety assessment of tumor necrosis factor antagonists during pregnancy: a review of the Food and Drug Administration database. J Rheumatol, 36(3):635-41. Griffiths CE, Strober BE, van de Ke…

Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

Overview The diagnosis of Paget’s disease or extramammary Paget’s is made when Paget cells are identified in histopathologic specimens from involved skin. The term Paget’s disease is used when the cutaneous lesion is identified inv…

Therapeutic Strategies in Dermatology

Impetigo: Key Points

Key Points Impetigo is a highly contagious superficial cutaneous infection by Staphylococcus aureus and/or Streptococcus pyogenes. Effective treatment is directed at both organisms. Secondary impetigo, or impetiginization, may complicate preexistin…

Therapeutic Strategies in Dermatology

Pyoderma Gangrenosum: Treatment

Treatment First-line therapy: The first-line therapy for pyoderma gangrenosum is comprised of two key elements: controlling inflammation and optimizing wound care. Inflammatory control may require systemic immunosuppression and/or the use of multip…

Dermatology Practical & Conceptual

Pigmented tumor in the nostril

Abstract A 64-year-old man was noted to have a single pigmented lesion in the nostril of his nose. Clinical examination revealed a 5 mm nodular growth and brown lesion. With a presumed clinical diagnosis of malignant skin tumor, a biopsy was perform…