Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Key Points

…ncluding the bone marrow and liver/spleen/lymphatic tissues Urticaria pigmentosa is a form of cutaneous mastocytosis most common in childhood, characterized by brown papules, plaques, or nodules, which may urticate when stroked. Patients with cut…

Therapeutic Strategies in Dermatology

Urticaria: References

References Khan DA. (2008) Chronic urticaria: diagnosis and management, Allergy Asthma Proc, 29: 439-446. Peroni A et al. (2010) Urticarial lesions: If not urticaria, what else? The differential diagnosis of urticaria. Part I, II, J Am Acad Derm, 62…

Therapeutic Strategies in Dermatology

Urticaria: Clinical Cases

…ases Case 1 12-year-old girl 3-day history of pruritic urticarial lesions on chest, back, and abdomen No associated symptoms of fever, shortness of breath 1 week ago: 2-day history of sore throat No medications Initial treatment Start lorata…

Therapeutic Strategies in Dermatology

Drug Eruptions: Key Points

…discussed here. Other specific drug-induced disorders such as urticaria, erythema multiforme, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and phototoxicity are discussed in other chapters. (See Urticaria and Erythema Multiforme….

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease): Initial Evaluation

…ophicans. Lymphocytoma Lymphocytoma typically presents as a solitary lesion. The earlobe, nipple, scrotum, and axillary folds are common sites of involvement. Differential diagnosis Urticaria Scleroderma…

Therapeutic Strategies in Dermatology

Cutaneous T-Cell Lymphoma/ Mycosis Fungoides: Overview

…ve). (c)  Side effects include erythema, irritant dermatitis, urticaria, telangiectasia, and reversible bone marrow depression with pancytopenia. Later stage cutaneous T-cell lymphoma Patients in this category are best treated in consultation with a…

Therapeutic Strategies in Dermatology

Urticaria Pigmentosa / Mastocytosis: Treatment

…lary steps H1 antihistamines can decrease itching, flushing, urticaria, and tachycardia. Both sedating and non-sedating antihistamines may offer some relief (diphenhydramine or hydroxyzine and cetirizine, respectively). Combination H1 and H2 antihis…

Therapeutic Strategies in Dermatology

Erythema Multiforme: References

References Shah KN, Honig PJ, Yan AC (2007) “Urticaria multiforme: a case series and review of acute annular urticarial hypersensitivity syndromes in children,” Pediatrics, 119;e1177. Hughey SL (2011) Approach to the hospitalized patient…

Therapeutic Strategies in Dermatology

Papular Urticaria: References

…rences Hernandez RG, Cohen BA (2006) Insect bite-induced hypersensitivity and the SCRATCH principles: a new approach to papular urticaria, Pediatrics, 18(1):e189-96. Shmidt E, Levitt J (2012) Dermatologic infestations, Int J Derm, 51(2):131-141….