Therapeutic Strategies in Dermatology

Cutaneous Allergic (Leukocytoclastic) Vasculitis: Overview

Overview In approximately 50% of cases, cutaneous leukocytoclastic vasculitis (LCV) is caused by associated disease or underlying infection, or by a chemical or drug. The therapeutic strategy is to treat the underlying disorder. Recreational cocaine…

Therapeutic Strategies in Dermatology

Leukocytoclastic Vasculitis: References

…tter DA, Pittelkow MR, Wada DA. (2012). Cutaneous small-vessel vasculitis associated with solid organ malignancies: the Mayo Clinic experience, 1996 to 2009, JAAD, 66(2):e55-65. Ting TV. (2014). Diagnosis and management of cutaneous vasculitis in chi…

Differential Diagnosis in Dermatopathology

Leukocytoclastic vasculitis vs. livedo vasculitis

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Differential Diagnosis in Dermatopathology

Allergic (leukocytoclastic) vasculitis vs. Septic vasculitis

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Therapeutic Strategies in Dermatology

Erysipelas/Cellulitis: Key Points

Key Points Erysipelas and cellulitis are infections of the dermis and subcutaneous layers of the skin that are rapidly progressive and are often accompanied by systemic signs, such as fever, leukocytosis, and elevated markers of systemic inflammat…

Therapeutic Strategies in Dermatology

Urticaria: Key Points

Key Points Urticaria is a very common disease with a lifetime prevalence of approximately 20%. Individual lesions of urticaria typically present for less than 24 hours; persistence of a lesion greater than 24 hours is suggestive of a different diag…

Therapeutic Strategies in Dermatology

Borreliosis (Lyme Disease): Key Points

Key Points Infection with various Borrelia species causes borreliosis, which may have cutaneous and systemic manifestations. This infection is transmitted through bites of the Ixodes species of ticks. Early Lyme disease (erythema chronicum migrans…

Therapeutic Strategies in Dermatology

Lupus: Key Points

Key Points Lupus is a disease that presents across a broad spectrum of cutaneous and systemic manifestations. It may be cutaneous-only or systemic with cutaneous manifestations; some patients with systemic lupus do not have cutaneous involvement. D…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

See Fig. 5.218 A&B. Figure 5.218 Vasculitis. A. Small vessel. B. Large vessel. Before a reasoned and reasonable method for diagnosis histopathologic of vasculitis in skin and subcutaneous fat can be formulated, a definition of vasculitis must…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Vasculitis?

….” Carlson JA, Mihm MC, Leboit PE. Cutaneous lymphocytic vasculitis: a definition, a review, and a proposed classification. Semin Diagn Pathol 1996;13(1):72–90. “Lymphocytic vasculitis (LV) is defined in different ways by differen…