Histologic Diagnosis of Inflammatory Skin Diseases

Xanthomas

Xanthomas Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Localized or widespread Individual lesions Macules, papules, plaques, and nodules Course Some lesions, e.g., eruptive xanthomas, involuting when serum lipi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

“Nine biopsies revealed a distinctive type of fibroma characterized by an organized pattern of interwoven fascicles of collagen bundles with a laminated or tortuous appearance, embedded in abundant mucin. A number of fibromas showed striking…

Dermatology Practical & Conceptual

Pigmented tumor in the nostril

Abstract A 64-year-old man was noted to have a single pigmented lesion in the nostril of his nose. Clinical examination revealed a 5 mm nodular growth and brown lesion. With a presumed clinical diagnosis of malignant skin tumor, a biopsy was perform…

Differential Diagnosis in Dermatopathology

Discussions

Epidermolytic hyperkeratosis and a plane wart share several findings histopathologic, among them being a papillated and thickened epidermis, hypergranulosis, and cells with pale cytoplasm within the epidermis. The terms “epidermolytic hyperker…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous Horn?

“Cutaneous horns may complicate solar keratoses, viral warts, seborrheic warts, squamous cell carcinomas, lichenoid keratoses, and basal cell carcinomas.” McKee PH. Tumors of the surface epithelium. In: Pathology of the Skin with Clinic…

Differential Diagnosis in Dermatopathology

Discussions

Verrucous seborrheic keratosis and verrucous epidermal nevus share several findings histopathologic, among them laminate and basket-woven orthokeratosis, an epidermis thinned in some foci and thickened in others, the presence sometimes of “hor…

Differential Diagnosis in Dermatopathology

Lichen sclerosus et atrophicus vs. Chronic radiation dermatitis

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Differential Diagnosis in Dermatopathology

Study By Disease

“Blue nevus” (Jadassohn-Tièche) (Quiz #360) “Blue nevus” (Jadassohn-Tièche) (Quiz #525) “Blue nevus” (Masson’s blue neuronevus) (Quiz #359) “Collagenous” nevus, papillary dermal type* (Quiz #11…

Differential Diagnosis in Dermatopathology

Verrucous seborrheic keratosis vs. Verrucous epidermal nevus

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…