Search Results for: vesicle

A Clinical Atlas of 101 Common Skin Diseases

Pemphigus Foliaceus

A blistering inflammatory disease in which acantholysis occurs in the upper part of the spinous zone or granular zone of the epidermis, the result of the process being flaccid blisters that give way to erosions and crusts accompanied by erythema….

Histologic Diagnosis of Inflammatory Skin Diseases

Arthropod assaults

…res differentiating: Insect “bites” differ clinically from Grover’s disease by the presence often of papulovesicles and vesicles, and of hemorrhagic crusts. Denominators in common: Yellow-brown, smooth-surfaced papules Features…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…sociated invariably with epidermal necrosis. A normal cornified layer with its basket-weave configuration indicates that the vesicle is only of a few days” duration. Although at first glance the vesicle seems to be entirely intraepidermal,…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…m a subepidermal vesicle. The “rule” that a subepidermal vesicle is more firmly distended than an intraepidermal vesicle is violated often, as evidenced by tense vesicles that are standard in varicella, miliaria crsytallina, and an…

Histologic Diagnosis of Inflammatory Skin Diseases

Hand-foot-and-mouth disease

…e from the mummified blister of ghosts of acantholytic mononucleate and multinucleate cells. Explosion of the intraepidermal vesicle results in formation of a subepidermal vesicle. Rarely is an intact blister of hand-foot-and-mouth disease…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…despite their being alike histopathologically. Note the fibrin in association with neutrophils in the incipient subepidermal vesicle. 10.19.15A: Vesicular dermatitis, subepidermal + 10.19.15B: Neutrophils and nuclear “dust” of…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

…nterpreted as true urtica, a condition devoid entirely of such “dust.” If, however, a purpuric papule or a fresh vesicle is present, biopsy of either of them will disclose not only nuclear “dust” of neutrophils in greater…