Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…s accumulate in dermal papillae and subepidermal spaces or in vesicles. Acantholytic cells appear in inflammatory conditions, such as pemphigus vulgaris, in neoplasms, such as squamous-cell carcinoma (the so-called pseudoglandular type), and in cysti…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…icarial stage, which often is preceding. At times, however, a vesicle of dermatitis herpetiformis may spring directly from what seems like normal skin. 10.19.11A: Vesicular dermatitis, subepidermal, neutrophils predominate + 10.19.11B: Numerous neutr…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…cases of infection by herpesvirus, beneath the intraepidermal vesicle typical of it are found venules with changes indistinguishable from those of leukocytoclastic vasculitis (Fig. 5.228 A&B), they being presumed to have been brought about by the…

Histologic Diagnosis of Inflammatory Skin Diseases

Hand-foot-and-mouth disease

…tered and discrete; sometimes linear Configuration of lesions Vesicles oblong and surrounded by a distinct rim of erythema Individual lesions Papules, papulovesicles, and, later, pustules; roof of blisters often gray Course Lesions usually disappear…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

…esion usually is a macule, papule (which may be scaly), papulovesicle, or vesicle. A pustule, such as in pustular psoriasis and suppurative infundibulitides/folliculitides, also is an appropriate lesion for harvest by biopsy. A pustule that represent…

Histologic Diagnosis of Inflammatory Skin Diseases

Mucha-Habermann disease

…sions Red macules and papules, purpuric and necrotic papules, vesicles, ulcers, and scars Course Sometimes transient, i.e., weeks, or lesions coming and going for years Variations clinical Pityriasis lichenoides acuta consists of red and purple papul…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…process pathologic of lichen planus. The lesions actually are vesicles, not bullae. Erosive lichen planus affects volar skin extensively by ulceration diffusely; mucous membranes often involved concurrently. Oral lichen planus of the buccal mucosa es…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…on” only for a spongiotic dermatitis manifested by tiny vesicles on the hands of patients who have florid dermatophytosis at another site, usually the feet, or for an analogue of that phenomenon such as widespread vesicles that appear subsequen…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…to enlarge. + Large collections of eosinophils in spongiotic vesicles = Incontinentia pigmenti + Collections of eosinophils in discrete loci of the epidermis = Toxic erythema of the newborn + Acantholytic cells in suprabasal spaces, surface epiderma…