Search Results for: vesicle

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…m a subepidermal vesicle. The “rule” that a subepidermal vesicle is more firmly distended than an intraepidermal vesicle is violated often, as evidenced by tense vesicles that are standard in varicella, miliaria crsytallina, and an…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…despite their being alike histopathologically. Note the fibrin in association with neutrophils in the incipient subepidermal vesicle. 10.19.15A: Vesicular dermatitis, subepidermal + 10.19.15B: Neutrophils and nuclear “dust” of…

Histologic Diagnosis of Inflammatory Skin Diseases

Hand-foot-and-mouth disease

…e from the mummified blister of ghosts of acantholytic mononucleate and multinucleate cells. Explosion of the intraepidermal vesicle results in formation of a subepidermal vesicle. Rarely is an intact blister of hand-foot-and-mouth disease…

Histologic Diagnosis of Inflammatory Skin Diseases

Selection of the Site

…nterpreted as true urtica, a condition devoid entirely of such “dust.” If, however, a purpuric papule or a fresh vesicle is present, biopsy of either of them will disclose not only nuclear “dust” of neutrophils in greater…

Histologic Diagnosis of Inflammatory Skin Diseases

Mucha-Habermann disease

…ma of the papillary dermis and vacuolar alteration along the dermoepidermal junction or of rupture of a tense intraepidermal vesicle. Some vesicles of Mucha-Habermann disease may be wholly intraepidermal, some wholly subepidermal, and some both…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…ytes. Features typical of a papule of lichen planus are not seen beneath a subepidermal blister of lichen planus because the vesicle is the result of acceleration remarkably of the fundamental process pathologic of lichen planus. The lesion evolves…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…or changes seen histopathologically, namely, a small collection of neutrophils within an epithelium or nonepithelium, a tiny vesicle caused by spongiosis, ballooning, or acantholysis, and a little cyst, usually an epidermal (infundibular) one, known…