Therapeutic Strategies in Dermatology

Superficial Fungal Infections: Therapy: Tinea versicolor

…atitis, pityriasis rosea, pityriasis alba, leprosy, syphilis, vitiligo, parapsoriasis, mycosis fungoides, anetoderma. Initial therapy Selenium sulfide shampoo (2%) is the most economical therapy and many treatment schedules are effective. Have the p…

Therapeutic Strategies in Dermatology

Dermatitis Herpetiformis: Treatment

…autoimmune diseases, including hypothyroidism (most common), vitiligo, Addison’s disease, in addition to celiac disease. A complete history and physical evaluation, including review of systems, is necessary to determine concomitant disease. Referral…

Histologic Diagnosis of Inflammatory Skin Diseases

Vitiligo

Vitiligo Synonyms Achroma vitiligo Presentation stereotypical Age and sex Young adults and women especially Distribution of lesions Localized, segmental, or widespread; often symmetric Individual lesions Macules and patches Course Protracted usually…

Histologic Diagnosis of Inflammatory Skin Diseases

Vitiligo

An inflammatory process that is idiopathic and results in depigmentation of the skin consequent to loss of melanocytes from the epidermis, and in whitening of hair that follows loss of melanocytes from the bulb of follicles….

Therapeutic Strategies in Dermatology

Melanoma: Treatment

Treatment Initial therapy First-line therapy: Surgical excision For diagnosis, complete excisional biopsy with minimal margins, pathologically evaluated at multiple levels to determine the tumor thickness, as well as to determine presence of ulcera…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Halo Phenomenon?

…17;s nevus, leukoderma acquisitum centrifugum, and perinevoid vitiligo. Although the condition is known eponymically for Sutton, who popularized it, Hebra actually was the first to describe it. A halo in the context of a Clark’s nevus or of any…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…tes in foci of subtle spongiosis as well as around a venule = Vitiligo  In an early lesion of vitiligo, such as the one shown here, lymphocytes are present in the upper part of the dermis and in the epidermis, where they induce a tad of spongiosis, a…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…sed melanin in the epidermis, as in confetti-sized lesions of vitiligo. Pinpoint purple macules (petechiae) are caused by erythrocytes extravasated in the papillary dermis, and larger spots marked by hemorrhage can be produced by trauma as in “…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Blaschkitis?

…ose being lichen striatus, lichen planus, lichen nitidus, and vitiligo. Genomic mosaicism also may help explain the occurrence, described by Grosshans and Marot, of lesions in the acquired relapsing and self-healing dermatoses that course unilaterall…