Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

Both somatic sensory and autonomic motor nerves are present in skin (Fig. 1.82). The somatic sensory system mediates sensations of pain, itch, temperature, light touch, discriminative touch, pressure, vibration, and proprioception. Nerves of the aut…

Differential Diagnosis in Dermatopathology

Discussions

Psoriasis on volar skin and dyshidrotic dermatitis—the latter a disease that virtually always is restricted to volar skin or skin immediately adjacent to it—often share findings histopathologic: scale-crusts, psoriasiform acanthosis, foc…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.22.1A: Vesicular dermatitis, intraepidermal, spongiotic + 10.22.1B: Hyphae in the cornified layer = Dermatophytosis Were there no hyphae present in the stratum corneum, the differential diagnosis also would include allergic cont…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.90.1A: Perivascular dermatitis, psoriasiform + 10.90.1B: Lymphocytes and neutrophils around venules, dilated tortuous capillaries in edematous dermal papillae, spongioform pustules, and tiers of neutrophil-containing mounds of p…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 11.15.1A: Vesicular dermatosis, subepidermal + 11.15.1B: Dermal papillae on volar skin preserved = Porphyria cutanea tarda ¬†Although venules and capillaries in the upper part of the dermis of porphyria cutanea tarda usually are rim…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthomas

…re arranged in nodules and sheets in a dome-shaped lesion near volar skin poor in epithelial structures of adnexa, the diagnosis is xanthoma tuberosum. If foamy histiocytes are present mostly in the upper half of the dermis of true volar skin, the di…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…us, congenital (Quiz #772) Melanocytic nevus, junctional, near volar skin (Quiz #440) Melanocytic nevus, junctional, on volar skin (Quiz #439) Melanoma (Quiz #6) Melanoma (Quiz #89) Melanoma (Quiz #306) Melanoma (Quiz #307) Melanoma (Quiz #308) Melan…

Histologic Diagnosis of Inflammatory Skin Diseases

Pitted keratolysis

Pitted keratolysis Synonyms Keratoma sulcatum Keratoma plantare sulcatum Keratolysis plantare sulcatum Presentation stereotypical Age and sex Particularly men with sweaty feet who wear occlusive footwear Distribution of lesions Soles, especially o…