Histologic Diagnosis of Inflammatory Skin Diseases

Nerves

…pressure are pictured in the subcutaneous fat at a site near volar skin. (From AB Ackerman, H Jacubovic. In: Moschella SL, Hurley HJ, eds. Dermatology, 3rd ed. Philadelphia: W.B. Saunders, 1992.) Meissner’s corpuscles (Fig. 1.84), lodged at th…

Differential Diagnosis in Dermatopathology

Discussions

Psoriasis on volar skin and dyshidrotic dermatitis—the latter a disease that virtually always is restricted to volar skin or skin immediately adjacent to it—often share findings histopathologic: scale-crusts, psoriasiform acanthosis, foc…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…fication are still covered by the original stratum corneum of volar skin. Note how deep in that pristine cornified layer hyphae are situated, an indication of how far down scraping must be carried in readiness for examination of scales in a KOH prepa…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…arrayed in staggered fashion = Psoriasis, fully developed  On volar skin, psoriasis often is associated with prominent spongiosis and, sometimes, spongiotic vesicles that release large amounts of serum into mounds of parakeratosis. In short, psoriasi…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…r dermatosis, subepidermal + 11.15.1B: Dermal papillae on volar skin preserved = Porphyria cutanea tarda  Although venules and capillaries in the upper part of the dermis of porphyria cutanea tarda usually are rimmed by homogeneous eosinophilic m…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthomas

…e arranged in nodules and sheets in a dome-shaped lesion near volar skin poor in epithelial structures of adnexa, the diagnosis is xanthoma tuberosum. If foamy histiocytes are present mostly in the upper half of the dermis of true volar skin, the dia…

Histologic Diagnosis of Inflammatory Skin Diseases

Study By Disease

…s, congenital (Quiz #772) Melanocytic nevus, junctional, near volar skin (Quiz #440) Melanocytic nevus, junctional, on volar skin (Quiz #439) Melanoma (Quiz #6) Melanoma (Quiz #89) Melanoma (Quiz #306) Melanoma (Quiz #307) Melanoma (Quiz #308) Melano…

Histologic Diagnosis of Inflammatory Skin Diseases

Pitted keratolysis

…face of a thick compactly-arranged cornified layer typical of volar skin Clumps of bacteria, cocci or bacilli, some in filamentous form, in the cornified layer Differential diagnosis clinical Tinea pedis often assumes arcuate and annular shapes, is…