Resolving Quandaries in Dermatology, Pathology & Dermatopathology


“Atrophoderma, or atrophia cutis. Atrophy of the skin may be quantitative or qualitative; idiopathic or symptomatic; diffused or circumscribed. Crocker gives this useful table: Pigmentosum Juvenilis Albidum Diffusum Senilis

Histologic Diagnosis of Inflammatory Skin Diseases

Pruritic urticarial papules and plaques of pregnancy

…cy Nurse’s late onset prurigo of pregnancy Presentation stereotypical Age and sex Primigravidas late in the third trimester; commencement earlier than that trimester and after parturition rarely Distribution of lesions Abdomen, buttocks, and t…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…reticular dermis, and obscures the junction of an acanthotic, somewhat jagged, surface epidermis. The surface of the lesion is flat because the surface of the epidermis is flat. Wickhamss striae are exaggerations of compact orthokeratosis that resid…

Histologic Diagnosis of Inflammatory Skin Diseases


…ers clinically from lichen planus by the presence of micaceous scale and Auspitz’s sign, and by the absence of polygonal outline of papules and of Wickhams striae Variations clinical Generalized pustular psoriasis (acute generalized pu…

Differential Diagnosis in Dermatopathology


Lichen planus and lichenoid secondary syphilis share several attributes histopathologic, among those being a lichenoid infiltrate composed largely of mononuclear inflammatory cells in company at times with melanophages, vacuolar alteration along the…

Dermatology Practical & Conceptual

Inguinal porokeratosis in a Japanese man

…periphery (Figure 4). The peripheral border of the white track showed light brown pigmentation, making the white track recognizable. There was no whitish linear structure corresponding to Wickhams striae often seen in lichen planus. A biopsy was tak…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen striatus

…n planus is purple, and individual papules are topped by white streaks arranged in a reticulated pattern, i.e., Wickhams striae. Psoriasis, when linear, is red, and lesions are covered by a gray-white scale. An inflammatory linear verrucous ep…

Differential Diagnosis in Dermatopathology

Lichen planus vs. Lichenoid secondary syphilis

An inflammatory process in pregnant women near term that consists of urticarial papules and plaques, especially on the trunk and particularly in association with lesions of striae atrophicantes, the lesions disappearing shortly after parturition….