Search Results for: xanthogranuloma

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

…seems to us to be a synonym for one manifestation of juvenile xanthogranuloma, an inflammatory condition in which lipophages predominate. One distinctive variant morphologic of lipophage, Touton’s giant cell, typified by a central amphophilic c…

Differential Diagnosis in Dermatopathology

Discussions

Necrobiosis lipoidica (diabeticorum) and necrobiotic xanthogranuloma are granulomatous diseases marked by widespread changes in the dermis and the panniculus adiposus. The processes pathologic spare the upper part of the dermis and may extend as dee…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…of collagen and extracellular deposits of lipid = Necrobiotic xanthogranuloma  Necrobiosis lipoidica and necrobiotic xanthogranuloma have features in common, among them lymphoplasmacytic infiltrates, granulomatous inflammation, and degeneration of co…

Differential Diagnosis in Dermatopathology

Discussions

…two columns preceding, one for attributes histopathologic of xanthogranulomas (childhood and adult) and the for reticulohistiocytic granuloma, a student could conclude that the two “granulomas” were separate and distinct from one another…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…neous diseases, namely, necrobiosis lipoidica and necrobiotic xanthogranuloma. Authors of current textbooks of dermatology, dermatopathology, and general pathology deem those diseases, as well as granuloma annulare and rheumatoid nodule, to be necrob…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…different from them as necrobiosis lipoidica and necrobiotic xanthogranuloma, both of which affect profoundly collagen and blood vessels). Error: Colloid is a distinct and distinctive substance. Reason: Colloid is nothing other than elastotic materi…

Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

…of inflammatory cells. Differential diagnosis histopathologic Xanthogranuloma may be indistinguishable at times from reticulohistiocytic granuloma. In examples stereotypical of lesions of xanthogranuloma developed fully, however, histiocytes have abu…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…+ 10.114.1B: Foamy histiocytes, many of them multinucleate = Xanthogranuloma, fully developed  Lymphocytes, plasma cells, and eosinophils are scattered among the predominant histiocytes, many of which are of Touton type, the stereotypical character…