Search Results for: xanthogranuloma

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Histiocytoses?

…d disorders of adults A. Normolipemic cutaneous xanthomatosis 1. Papular 2. Generalized xanthelasma 3. Solitary and eruptive xanthogranuloma 4. Necrobiotic xanthogranuloma 5. Xanthoma disseminatum 6. Subcutaneous xanthomatosis B. Multicentric…

Differential Diagnosis in Dermatopathology

Discussions

…a, hypocomplementemia, hyperlipidemia, and cryoglobulinemia have been noted episodically in persons afflicted by necrobiotic xanthogranuloma. Whether necrobiotic xanthogranuloma can occur in the absence of paraproteinemia is not established, but we…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…2B: Numerous multinucleate histiocytes, many of them Touton type, and lymphoid follicles + 10.68.2C + 10.68.2D = Necrobiotic xanthogranuloma This presentation of necrobiotic xanthogranuloma is exceptional because there are no large zones of…

Differential Diagnosis in Dermatopathology

Discussions

…s a rule, do not resolve without treatment. No abnormalities of serum lipids are found in either children or adults who bear xanthogranulomas. On examination histopathologic of a solitary nodule of a xanthogranuloma early in its course chronologic,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…red nodules or plaques, primarily involving the face and, less frequently, the trunk and extremities. … Histologically, xanthogranulomatous features with hyaline necrosis or necrobiosis are present.” Burdick AE, Sanchez J, Elgart GW….

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…atosus, simply is a manifestation morphologic of lupus erythematosus. Error: Reticulohistiocytic granuloma is different from xanthogranuloma. Reason: It is a variant of xanthogranuloma distinguished by a characteristic appearance cytopathologic,…

Histologic Diagnosis of Inflammatory Skin Diseases

Reticulohistiocytic granuloma

…with abundant pale amphophilic cytoplasm, and scattered among them lymphocytes, plasma cells, neutrophils, and eosinophils = Xanthogranuloma (reticulohistiocytic granuloma), fully developedReticulohistiocytic granuloma is that variant of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…+ 10.114.2B: Foamy histiocytes, some of them multinucleate, and a sprinkling of lymphocytes, eosinophils, and neutrophils = Xanthogranuloma, fully developed Early in its course, xanthogranuloma consists of a monomorphous infiltrate of histiocytes…