Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

…eoplasia with cytomorphologic features of malignancy, namely, carcinoma in situ lesions, by surgical pathologists. If one looks for an equivalent lesion to the so-called dysplastic (carcinoma in situ) lesions of epithelial tissue in melanocytic neopl…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…the vessel walls by lymphocytes. In addition, the endothelial cells are swollen, narrowing the lumen of the affected vessels.” Szymanski FJ. Pityriasis lichenoides et varioliformis acuta. Arch Dermatol 1959;79:7–16. “Pityriasis li…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Spongiform Pustular Diseases?

…ave migrated into the soaked epidermis, destroying epithelial cells by invading them or going between them.” Kogoj F. Die spungiforme (schwammartige) Pustel. Dermatol Wochnschr 1938;107:1485-87. “Of all the listed features, only the sp…

Dermatology Practical & Conceptual

Glomangiosarcoma in the shoulder of a 51-year-old man

…s performed. Histopathological findings Shave biopsy showed a cellular neoplasm with a multinodular growth pattern in the dermis (Figure 1A). The neoplasm was very cellular and consisted of round, ovoid and spindle cells with moderate nuclear atypia…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…oid type with numerous foreign body and Langhans’ giant cells were the dominating features [of metastatic Crohn’s disease]. In accordance with previous results, we found vascular involvement in 2 cases, manifested as granulomatous perivas…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…as well as in the upper part of the dermis Perivascular mixed-cell infiltrate of lymphocytes and neutrophils Patchy infiltrates of neutrophils in lobules in the subcutaneous fat and dispersed also among collagen bundles in the lower part of the retic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

…micron, will ensure cure, i.e., the person will never die of metastatic melanoma. If, however, a melanoma, no matter how thin, already has metastasized by the time the neoplasm is excised in toto, the patient is likely doomed to die of metastatic me…

Differential Diagnosis in Dermatopathology

Discussions

…hologic develop in them. Those range from formation of “squamous eddies” to development of nuclear abnormalities that may simulate vaguely the kind seen in squamous-cell carcinoma. Of the three major patterns of seborrheic keratoses, name…