Differential Diagnosis in Dermatopathology

Discussions

…s hyperplasia may be misinterpreted clinically as a basal-cell carcinoma because both conditions have a slightly elevated border and a central dell. In basal-cell carcinoma, however, the depression in the center usually represents an erosion or ulcer…

Dermatology Practical & Conceptual

The so-called dysplastic nevus is not dysplastic at all

Editorial In a recent two-part essay entitled “The dysplastic nevus: from historical perspective to management in the modern era” published in the Journal of American Academy of Dermatology, Duffy and Grossman concluded, following compre…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…i in the lumen in the context of an infiltrate of inflammatory cells. In the vast majority of instances, the cells are neutrophils, e.g., in leukocytoclastic vasculitis, septic vasculitis, and livedo vasculitis. Rarely, lymphocytes monopolize the inf…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Spongiform Pustular Diseases?

“The pustule I have designated spongiform (spongelike) was markedly and impressively seen in acrodermatitis continua of Hallopeau. It is composed of leukocytes that have migrated into the soaked epidermis, destroying epithelial cells by inva…

Dermatology Practical & Conceptual

Glomangiosarcoma in the shoulder of a 51-year-old man

…as performed. Histopathological findings Shave biopsy showed a cellular neoplasm with a multinodular growth pattern in the dermis (Figure 1A). The neoplasm was very cellular and consisted of round, ovoid and spindle cells with moderate nuclear atypia…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…both together in the context of an infiltrate of inflammatory cells. The definition of vasculitis of small vessels in skin is different from that of vasculitis of large vessels in the subcutaneous fat, in which the presence of inflammatory cells in…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…ease. Arch Dermatol 1982;118:1006–09. McLelland J, Griffin SM. Metastatic Crohn’s disease of the umbilicus. Clin Exp Dermatol 1996;21:318–9. Shum DT, Guenther L. Metastatic Crohn’s disease. Case report and review of the literature. Arch D…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

…1 micron, will ensure cure, i.e., the person will never die of metastatic melanoma. If, however, a melanoma, no matter how thin, already has metastasized by the time the neoplasm is excised in toto, the patient is likely doomed to die of metastatic m…