Differential Diagnosis in Dermatopathology

Seborrheic keratosis, acanthotic type vs. Eccrine poroma

…cies in a remarkably poignant way that told of the anguish of metastatic carcinoma and conveyed the madness of factitious dermatitis. In this volume we have set out to produce an atlas of dermatology that is a work of art as well as a work of substan…

Differential Diagnosis in Dermatopathology

Discussions

…ceous hyperplasia may be misinterpreted clinically as a basal-cell carcinoma because both conditions have a slightly elevated border and a central dell. In basal-cell carcinoma, however, the depression in the center usually represents an erosion or u…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Spongiform Pustular Diseases?

…ave migrated into the soaked epidermis, destroying epithelial cells by invading them or going between them.” Kogoj F. Die spungiforme (schwammartige) Pustel. Dermatol Wochnschr 1938;107:1485-87. “Of all the listed features, only the sp…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Mucha-Habermann Disease a Lymphocytic Vasculitis?

…the vessel walls by lymphocytes. In addition, the endothelial cells are swollen, narrowing the lumen of the affected vessels.” Szymanski FJ. Pityriasis lichenoides et varioliformis acuta. Arch Dermatol 1959;79:7–16. “Pityriasis li…

Dermatology Practical & Conceptual

Dermoscopic clues to diagnose acantholytic dyskeratosis

…include both benign and malignant lesions, such as cutaneous squamous-cell carcinoma, verrucal keratosis, plantar hyperkeratosis, hair follicle changes, panniculitis, and photosensitivity [2], along with widespread eruptions with histologic features…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

…oid type with numerous foreign body and Langhans’ giant cells were the dominating features [of metastatic Crohn’s disease]. In accordance with previous results, we found vascular involvement in 2 cases, manifested as granulomatous perivas…

Dermatology Practical & Conceptual

Glomangiosarcoma in the shoulder of a 51-year-old man

…s performed. Histopathological findings Shave biopsy showed a cellular neoplasm with a multinodular growth pattern in the dermis (Figure 1A). The neoplasm was very cellular and consisted of round, ovoid and spindle cells with moderate nuclear atypia…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

…as well as in the upper part of the dermis Perivascular mixed-cell infiltrate of lymphocytes and neutrophils Patchy infiltrates of neutrophils in lobules in the subcutaneous fat and dispersed also among collagen bundles in the lower part of the retic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wide and Deep Excision for Melanoma?

…micron, will ensure cure, i.e., the person will never die of metastatic melanoma. If, however, a melanoma, no matter how thin, already has metastasized by the time the neoplasm is excised in toto, the patient is likely doomed to die of metastatic me…