Histologic Diagnosis of Inflammatory Skin Diseases

Linear IgA dermatosis

…of dermatitis herpetiformis and simulators of it, acantholytic cells may appear in the lower part of the epidermis and in the blister itself. Presumably, the acantholytic cells come into being as a consequence of enzymes released by countless neutrop…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ure of it 2. Step sections do not reveal a cyst 3. Cornified cells in the cyst are arranged in delicate laminate fashion 3. Cornified cells in cystic structures are arranged compactly 4. Rete ridges protrude from infundibular epithelium that line…

Differential Diagnosis in Dermatopathology

Discussions

These two common cutaneous cysts have several features in common, namely, lining of stratified squamous epithelium and cornified cells in their cavity. We name cysts according to the normal epithelial structure of skin that the lining of the cyst re…

Differential Diagnosis in Dermatopathology

Images

Dilated pore Pilar sheath acanthoma

Differential Diagnosis in Dermatopathology

Discussions

Distinction histopathologic between lichen planus-like keratosis and most solar keratosis is not difficult in some instances. When, however, a solar keratosis is accompanied by lichenoid infiltrates of lymphocytes, it may have many attributes in com…

Differential Diagnosis in Dermatopathology

Discussions

Nevus verrucosus and acanthosis nigricans are processes that affect the papillary dermis and the epidermis. Both conditions may display hyperkeratosis, epidermal hyperpigmentation, papillomatosis, melanophages, and an increased number of fibrocytes…