Histologic Diagnosis of Inflammatory Skin Diseases

Scar

Scar Synonyms Cicatrix Presentation stereotypical Age and sex Any age and both sexes Distribution of lesions Usually localized, but sometimes widespread Configuration of lesions Linear, as in a surgical wound Round, as a consequence of an ulcer ind…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Spitz’s Nevus, Compound Type Melanoma 1. Symmetric 1. Asymmetric 2. Sharp circumscription 2. Poor circumscription 3. Maturation of melanocytes (decrease in size of aggregations and of nuclei) with descent progressive 3. No maturation w…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphadenosis benigna cutis

…bite” and assaults by other arthropods may be identical. Spitz’s nevus often presents itself as a pink, red, or orange papule. Mastocytoma often has a yellow cast and urticates when irritated mechanically by virtue of liberation of histam…

Differential Diagnosis in Dermatopathology

Images

Spitz’s Nevus, Compound Type Melanoma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatofibroma Desmoplastic Spitz’s nevus 1. Acanthotic epidermis often associated with induction of folliculo-sebaceous units 1. Little or no acanthosis; no induction of folliculo-sebaceous units 2. Epidermis often thinned above the cen…

Differential Diagnosis in Dermatopathology

Images

Dermatofibroma Desmoplastic Spitz’s nevus

Differential Diagnosis in Dermatopathology

Discussions

A proliferation of keratocytes that simulates squamous-cell carcinoma and authentic squamous-cell carcinoma itself have findings histopathologic in common, including epithelial cells that cornify, nuclei of epithelial cells that are not entirely typ…