Search Results for: spitz-like nevus

Differential Diagnosis in Dermatopathology

Xanthogranuloma vs. Reticulohistiocytic granuloma

Papules, nodules, and tumors that, on gross examination, are usually skin colored and, on histopathologic examination, consist of an epithelium-lined sac that contains fluid, cells, or both in the case of true cysts and of cysts that are associated…

Differential Diagnosis in Dermatopathology

Discussions

…, a phenomenon known as Darier’s sign. A solitary lesion of juvenile xanthogranuloma may be confused clinically with a Spitz’s nevus. Each may be an orange, smooth-surfaced papule. In contrast to the expression in juvenile,…

Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…is of those so-called blue nevi that are associated with “collagenization,” and in the reticular dermis of those Spitz’s nevi and melanomas that are characterized by desmoplasia, which is a synonym for fibroplasia that accompanies…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign and Malignant Cells?

…st is the recognition that cells of a benign neoplasm may have startlingly large and pleomorphic nuclei, e.g., those of some Spitz nevi and of ancient Miescher’s nevi, and in reverse, cells of some malignant neoplasms may display remarkably…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphadenosis benigna cutis

…e affected, primary carcinoma must be considered. Tick “bite” and assaults by other arthropods may be identical. Spitz’s nevus often presents itself as a pink, red, or orange papule. Mastocytoma often has a yellow cast and…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Spitz’s Nevus, Compound Type Melanoma 1. Symmetric 1. Asymmetric 2. Sharp circumscription 2. Poor circumscription 3. Maturation of melanocytes (decrease in size of aggregations and of nuclei) with descent progressive 3. No maturation with…

Differential Diagnosis in Dermatopathology

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Spitz’s Nevus, Compound Type Melanoma

Differential Diagnosis in Dermatopathology

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Dermatofibroma Desmoplastic Spitz’s nevus

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatofibroma Desmoplastic Spitz’s nevus 1. Acanthotic epidermis often associated with induction of folliculo-sebaceous units 1. Little or no acanthosis; no induction of folliculo-sebaceous units 2. Epidermis often thinned above the center…