Histologic Diagnosis of Inflammatory Skin Diseases

Scar

…;collagenization,” and in the reticular dermis of those Spitz’s nevi and melanomas that are characterized by desmoplasia, which is a synonym for fibroplasia that accompanies a neoplasm. Parenthetically, fibroplasia is a synonym for fibros…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphadenosis benigna cutis

…ite” and assaults by other arthropods may be identical. Spitz’s nevus often presents itself as a pink, red, or orange papule. Mastocytoma often has a yellow cast and urticates when irritated mechanically by virtue of liberation of histami…

Differential Diagnosis in Dermatopathology

Images

Dermatofibroma Desmoplastic Spitz’s nevus

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Dermatofibroma Desmoplastic Spitz’s nevus 1. Acanthotic epidermis often associated with induction of folliculo-sebaceous units 1. Little or no acanthosis; no induction of folliculo-sebaceous units 2. Epidermis often thinned above the cen…

Differential Diagnosis in Dermatopathology

Images

Spitz’s Nevus, Compound Type Melanoma…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Spitz’s Nevus, Compound Type Melanoma 1. Symmetric 1. Asymmetric 2. Sharp circumscription 2. Poor circumscription 3. Maturation of melanocytes (decrease in size of aggregations and of nuclei) with descent progressive 3. No maturation w…

Differential Diagnosis in Dermatopathology

Discussions

…rsistent melanocytic nevi following partial surgical removal; Spitz’s nevi; ancient nevi; and melanocytic nevi on special sites, such as the breast (especially nipple and areola), genitalia, perianal region, umbilicus, and intertriginous region…